Enzymatic synthesis of Tinuvin

Utilize este identificador para referenciar este registo: https://hdl.handle.net/1822/13562

Título:	Enzymatic synthesis of Tinuvin
Autor(es):	Schroeder, M. Pereira, Luciana Rodríguez Couto, S. Erlacher, Angelika Schoening, K.-U. Paulo, Artur Cavaco Guebitz, G. M.
Palavras-chave:	Laccase Oxidative coupling Tinuvin Trametes hirsuta Biotransformation
Data:	Jun-2007
Editora:	Elsevier 1
Revista:	Enzyme and Microbial Technology
Resumo(s):	Coupling of 3-(3-tert-butyl-4-hydroxyphenyl) propionic acid methylester to 1H-benzotriazole using a laccase from Trametes hirsuta was studied. The potentially resulting coupling product Tinuvin 1130 is an important UV-absorber used in polymer based materials. Oxidation of the phenol by the laccase led to homomolecular coupling reactions while the laccase did not attack 1H-benzotriazole. Due to the homomolecular reaction of the phenol in the presence of laccase coupling of phenol and 1H-benzotriazole was only observed when 1H-benzotriazole was applied in four-fold molar excess. The reaction was monitored by UV/vis spectroscopy, TLC and MS (ion trap) analysis. Coupling of 1H-benzotriazole took place in ortho position according to the postulated mechanism.
Tipo:	Artigo
URI:	https://hdl.handle.net/1822/13562
DOI:	10.1016/j.enzmictec.2006.11.026
ISSN:	0141-0229
Versão da editora:	http://www.sciencedirect.com/science/article/pii/S0141022906005850
Arbitragem científica:	yes
Acesso:	Acesso aberto
Aparece nas coleções:	DET/2C2T - Artigos em revistas internacionais com arbitragem científica