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https://hdl.handle.net/1822/11949
Título: | Antimicrobial and anti-adhesive potential of a biosurfactant Rufisan produced by Candida lipolytica UCP 0988 |
Autor(es): | Rufino, R. D. Luna, J. M. Sarrubbo, L. A. Rodrigues, L. R. Teixeira, J. A. Takaki, G. M. Campos |
Palavras-chave: | Candida lipolytica Biosurfactant Antimicrobial Anti-adhesive |
Data: | Mai-2011 |
Editora: | Elsevier 1 |
Revista: | Colloids and Surfaces B: Biointerfaces |
Citação: | RUFINO, R. D. [et al.] - Antimicrobial and anti-adhesive potential of a biosurfactant Rufisan produced by Candida lipolytica UCP 0988. “Colloids and Surfaces B : Biointerfaces” [Em linha]. 84:1 (Maio 2011) 1-5. [Consult. 24 Mar. 2011]. Disponível em WWW:< URL:http://www.sciencedirect.com/science/article/pii/S0927776510006107>. ISSN 0927-7765. |
Resumo(s): | In the last years, researches developed with biosurfactants for application in the medical area have been revealing the promising biological activities of these biomolecules. In this work the antimicrobial and anti-adhesive properties of a biosurfactant Rufisan isolated from the yeast Candida lipolytica UCP 0988, growth in a medium supplemented with ground nut refinery residue was determined against several microorganisms. The biosurfactant was able to reduce the water surface tension from 70 to 25.3mN/m and showed a critical micelle concentration (CMC) of 0.03%. The biosurfactant was isolated after 72 h of fermentation and was tested in concentrations varying from 0.75 to 12 mg/l. The highest antimicrobial activities were observed against Streptococcus agalactiae, Streptococcus mutans, Streptococcus mutans NS, Streptococcus mutans HG, Streptococcus sanguis 12, Streptococcus oralis J22 at a concentration superior to the biosurfactant critical micelle concentration. Moreover, the biosurfactant showed anti-adhesive activity against most of the microorganisms tested. As far as we know, this is the first compilation of data on antimicrobial and anti-adhesive activities of a biosurfactant obtained from a Candida strain against such a broad group of microorganisms. The results obtained in this work showed that the biosurfactant from C. lipolytica is a potential antimicrobial and/or anti-adhesive agent for several biomedical applications |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/11949 |
DOI: | 10.1016/j.colsurfb.2010.10.045 |
ISSN: | 0927-7765 |
Versão da editora: | http://www.sciencedirect.com/ |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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Rufino_2011.pdf | Rufino_2011 | 166,86 kB | Adobe PDF | Ver/Abrir |