Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/89953
Título: | Deep eutectic solvents as suitable solvents for lipase-catalyzed transesterification reactions |
Autor(es): | Noro, Jennifer Martins Cabo, Joana Freitas, David S. Roque, Catarina S. de Castro, Mariana Cavaco-Paulo, Artur Silva, C. |
Palavras-chave: | biocatalysis deep eutectic solvent glucose esters lipase transesterification |
Data: | 2023 |
Editora: | Wiley |
Revista: | Chemsuschem |
Citação: | Noro, J., Cabo, J., Freitas, D. S., Roque, C. S., de Castro, M., Cavaco‐Paulo, A., & Silva, C. (2023, August 9). Deep Eutectic Solvents as Suitable Solvents for Lipase‐Catalyzed Transesterification Reactions. ChemSusChem. Wiley. http://doi.org/10.1002/cssc.202300615 |
Resumo(s): | In this work, three deep eutectic mixtures (DES 1: choline chloride/urea; DES 2: choline chloride/glycerol; and DES 3: tetrabutylammonium bromide/imidazole) were investigated as mediums for the synthesis of glucose laurate and glucose acetate. Aiming to achieve a greener and more sustainable approach, the synthesis reactions were catalyzed by lipases from Aspergillus oryzae (LAO), Candida rugosa (LCR), and porcine pancreas (LPP). The hydrolytic activity of lipases against p-nitrophenyl hexanoate revealed no evidence of enzyme inactivation when DES were used as medium. Regarding the transesterification reactions, combining LAO or LCR with DES 3 resulted in the efficient production of glucose laurate (from glucose and vinyl laurate) (conversion >60 %). The best result for LPP was observed in DES 2, with 98 % of product production after 24 hours of reaction. When replacing vinyl laurate by a smaller hydrophilic substrate, vinyl acetate, a distinct behavior was observed. LCR and LPP performed better in DES 1, yielding more than 80 % of glucose acetate after 48 hours of reaction. The catalytic activity of LAO was less pronounced, reaching only nearly 40 % of product in DES 3. The results highlight the potential of combining biocatalysis with greener and environmentally-safer solvents, for the synthesis of differentiated chain-length sugar fatty acid esters (SFAE). |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/89953 |
DOI: | 10.1002/cssc.202300615 |
ISSN: | 1864-5631 |
e-ISSN: | 1864-564X |
Versão da editora: | https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cssc.202300615 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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ChemSusChem - 2023 - Noro - Deep Eutectic Solvents as Suitable Solvents for Lipase‐Catalyzed Transesterification Reactions.pdf | 609,21 kB | Adobe PDF | Ver/Abrir |