Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/7395

TitleModelling diffusivity in porous polymeric membranes with an intermediate layer containing microbial cells
Author(s)Mota, M.
Yelshin, Alexander
Fidaleo, Marcello
Flickinger, Michael C.
KeywordsDiffusion
Microporous membrane
Immobilised cells
Modelling
Packing
Mass transfer
Issue date2007
PublisherElsevier B.V.
JournalBiochemical Engineering Journal
Citation"Biochemical Engineering Journal". ISSN 1369-703X. 37:3 (2007) 285-293.
Abstract(s)Three-layer systems (membrane – composite layer (cells + polymer) – membrane) are important in different biochemical applications. Models of latex layered-membranes were evaluated and compared with experimental data in order to predict the diffusivity of substrates in the composite layer containing living E.coli microbial cells. Diffusivity predictions are dependent on the presence or the absence of a ‘skin’ layer, on the degree of polymer particle coalescence and on the thickness of each layer. Simulations with layered models were made to identify the dominant mechanisms in the three-layer system. It was found that the layered system is sensitive to the latex coatings porosity when the composite layer occupies less than 50% of the total membrane system thickness. Whenever the control of polymer particle coalescence and of the layers (coating/composite layer) thickness may be achieved, multi-layer systems presenting a wide range of relative diffusion conductivities may be built for different types of living cells and for a wide variety of practical applications. The diffusivity of the latex layer is proportional to the square of latex porosity.
TypeArticle
URIhttp://hdl.handle.net/1822/7395
DOI10.1016/j.bej.2007.05.008
ISSN1369-703X
Peer-Reviewedyes
AccessOpen access
Appears in Collections:CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series

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