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https://hdl.handle.net/1822/67885| Título: | Genetic interaction of CTLA-4 with HLA-DR15 in multiple sclerosis patients |
| Autor(es): | Alizadeh, Mehdi Babron, Marie-Claude Birebent, Brigitte Matsuda, Fumihiko Quelvennec, Erwann Liblau, Roland Cournu-Rebeix, Isabelle Momigliano-Richiardi, Patricia Sequeiros, Jorge Yaouanq, Jacqueline Genin, Emmanuelle Vasilescu, Alexandre Bougerie, Héloise Trojano, Maria Martins Silva, Berta Maciel, P. Clerget-Darpoux, Françoise Clanet, Michel Edan, Gilles Fontaine, Bertrand Semana, Gilbert |
| Palavras-chave: | Abatacept Antigens, CD Antigens, Differentiation CTLA-4 Antigen Cohort Studies DNA Primers Genetic Predisposition to Disease HLA-DR Antigens HLA-DR Serological Subtypes Humans Immunoblotting Multiple Sclerosis Polymerase Chain Reaction Polymorphism, Genetic Promoter Regions, Genetic Immunoconjugates |
| Data: | Jul-2003 |
| Editora: | Wiley |
| Revista: | Annals of Neurology |
| Citação: | Alizadeh, M., Babron, M. C., Birebent, B., Matsuda, F., Quelvennec, E., Liblau, R., ... & Genin, E. (2003). Genetic interaction of CTLA‐4 with HLA‐DR15 in multiple sclerosis patients. Annals of neurology, 54(1), 119-122 |
| Resumo(s): | Multiple sclerosis is a chronic inflammatory disease of the central nervous system with a genetic component. Until now, the more consistent association with the disease is found with the major histocompatibility complex, especially HLA-DRB1*1501-DQB1*0602 haplotype. In this report, we demonstrate the interaction of Cytotoxic T Lymphocyte-associated antigen 4 (CTLA-4 [CD152]) gene with DRB1*15 haplotype in multiple sclerosis genetic susceptibility. Our data were obtained from two European independent family-based studies including 610 multiple sclerosis family trios. Ann Neurol 2003;54:119-122 |
| Tipo: | Artigo |
| URI: | https://hdl.handle.net/1822/67885 |
| DOI: | 10.1002/ana.10617 |
| ISSN: | 0364-5134 |
| e-ISSN: | 1531-8249 |
| Versão da editora: | https://onlinelibrary.wiley.com/doi/full/10.1002/ana.10617 |
| Arbitragem científica: | yes |
| Acesso: | Acesso restrito UMinho |
| Aparece nas coleções: |
Ficheiros deste registo:
| Ficheiro | Descrição | Tamanho | Formato | |
|---|---|---|---|---|
| Alizadeh-2003-Genetic-interaction-ofctla--with-hl.pdf Acesso restrito! | 60,13 kB | Adobe PDF | Ver/Abrir |
