Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/58887

TitleCandida sp. infections in patients with Diabetes mellitus
Author(s)Rodrigues, Célia F.
Rodrigues, M. Elisa
Henriques, Mariana
KeywordsCandida
biofilms
diabetes
medical devices
candidiasis
metabolic disorder
hyperglycemia
infection
Issue date10-Jan-2019
PublisherMultidisciplinary Digital Publishing Institute (MDPI)
JournalJournal of Clinical Medicine
CitationRodrigues, Célia F.; Rodrigues, M. Elisa; Henriques, Mariana, Candida sp. infections in patients with Diabetes mellitus. Journal of Clinical Medicine, 8(1), 2019
Abstract(s)Candidiasis has increased substantially worldwide over recent decades and is a significant cause of morbidity and mortality, especially among critically ill patients. Diabetes mellitus (DM) is a metabolic disorder that predisposes individuals to fungal infections, including those related to Candida sp., due to a immunosuppressive effect on the patient. This review aims to discuss the latest studies regarding the occurrence of candidiasis on DM patients and the pathophysiology and etiology associated with these co-morbidities. A comprehensive review of the literature was undertaken. PubMed, Scopus, Elseviers ScienceDirect, and Springers SpringerLink databases were searched using well-defined search terms. Predefined inclusion and exclusion criteria were applied to classify relevant manuscripts. Results of the review show that DM patients have an increased susceptibility to Candida sp. infections which aggravates in the cases of uncontrolled hyperglycemia. The conclusion is that, for these patients, the hospitalization periods have increased and are commonly associated with the prolonged use of indwelling medical devices, which also increase the costs associated with disease management.
TypeArticle
URIhttp://hdl.handle.net/1822/58887
DOI10.3390/jcm8010076
ISSN2077-0383
e-ISSN2077-0383
Publisher versionhttps://www.mdpi.com/journal/jcm
Peer-Reviewedyes
AccessOpen access
Appears in Collections:CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series

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