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|Title:||Osteoconductive scaffolds obtained by means of in situ surface functionalization of wet-spun fibre meshes for bone regeneration applications|
|Author(s):||Rodrigues, M. T.|
Leonor, I. B.
Viegas, C. A. A.
Dias, I. R.
Gomes, Manuela E.
Reis, R. L.
|Keywords:||Goat marrow stromal cells|
|Publisher:||Mary Ann Liebert Inc.|
|Journal:||Tissue Engineering. Part A|
|Citation:||Rodrigues M. T., Leonor I. B., Viegas C. A. A., Dias I. R., Gomes M. E., Reis R. L. Osteoconductive scaffolds obtained by means of in situ surface functionalization of wet-spun fibre meshes for bone regeneration applications, Tissue Engineering Part A, Vol. 14, Issue 5, pp. 765-765, 2008|
|Abstract(s):||The success of bone tissue engineering (TE) strategies is strongly dependent on the development of new synthetic materials com- bining osteoconductive, osteoinductive and osteogenic properties. Recent studies suggest that biomaterials incorporating silanol groups promote and maintain osteogenesis with or without bio- logical stimuli. This study aims to evaluate the osteoconductivity and osteogenic properties of novel wet-spun fibre mesh scaffolds of SPCL (blend of starch with polycaprolactone) with or without superficial functionalized silanol (Si-OH) groups by seeding/culturing them with goat marrow stromal cells (GBMCs)|
|Access:||Restricted access (UMinho)|
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