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TitleThe neurobiological hypothesis of neurotrophins in the pathophysiology of schizophrenia: A meta-analysis
Author(s)Rodrigues-Amorim, Daniela
Rivera-Baltanás, Tania
Peixoto, João Miguel Seiça Bessa
Sousa, Nuno
Vallejo-Curto, María de Carmen
Rodríguez-Jamardo, Cynthia
de Las Heras, María Elena
Díaz, Roberto
Agís-Balboa, Roberto Carlos
Olivares, J. M.
Spuch, Carlos
Issue dateNov-2018
JournalJournal of Psychiatric Research
CitationRodrigues-Amorim, D., Rivera-Baltanás, T., Bessa, J., Sousa, N., et. al. (2018). The neurobiological hypothesis of neurotrophins in the pathophysiology of schizophrenia: A meta-analysis. Journal of psychiatric research, 106, 43-53
Abstract(s)Schizophrenia is associated with patterns of aberrant neurobiological circuitry. The disease complexity is mirrored by multiple biological interactions known to contribute to the disease pathology. One potential contributor is the family of neurotrophins which are proteins involved in multiple functional processes in the nervous system, with crucial roles in neurodevelopment, synaptogenesis and neuroplasticity. With these roles in mind, abnormal neurotrophin profiles have been hypothesized to contribute to the pathology of schizophrenia.
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Appears in Collections:ICVS - Artigos em revistas internacionais / Papers in international journals

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