Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/57897

TitleNeurodevelopment impact of CO2-pneumoperitoneum in neonates: experimental study in a rat model
Author(s)Miranda, Alice Augusta Macedo
Roque, Susana
Pêgo, José M.
Correia-Pinto, Jorge
KeywordsAnimals
Carbon Dioxide
Cytokines
Female
Inflammation
Neurodevelopmental Disorders
Pneumoperitoneum, Artificial
Pregnancy
Rats, Sprague-Dawley
Stress, Physiological
Laparoscopy
Carbon-dioxide pneumoperitoneum
Neurodevelopment
Cytokine
Interleukin
Issue dateJan-2018
PublisherElsevier
JournalJournal of Surgical Research
CitationMiranda, A., Roque, S., Pêgo, J. M., & Correia-Pinto, J. (2018). Neurodevelopment impact of CO 2-pneumoperitoneum in neonates: experimental study in a rat model. Journal of Surgical Research, 221, 293-303
Abstract(s)Laparoscopy is becoming more common in neonates. However, concerns remain about the impact of the carbon-dioxide (CO2)-insufflation over the neonatal brain. We aim to evaluate the peripheral (serum) and central (cerebrospinal fluid [CSF]) cytokine response after neonatal CO2-pneumoperitoneum and its impact over neurodevelopmental milestones acquisition and long-term behavioral outcomes.
TypeArticle
URIhttp://hdl.handle.net/1822/57897
DOI10.1016/j.jss.2017.09.014
ISSN0022-4804
e-ISSN1095-8673
Publisher versionhttps://www.sciencedirect.com/science/article/pii/S002248041730611X
Peer-Reviewedyes
AccessEmbargoed access (3 Years)
Appears in Collections:ICVS - Artigos em Revistas Internacionais com Referee

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