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TitleCommercial products for osteochondral tissue repair and regeneration
Author(s)Bicho, Diana Stefania Faria
Pina, Sandra Cristina Almeida
Reis, R. L.
Oliveira, J. M.
KeywordsOsteochondral regeneration
Commercial products
Bone, cartilage, and osteochondral regeneration
Issue dateApr-2018
JournalAdvances in Experimental Medicine and Biology
CitationBicho D., Pina S., Reis R. L., Oliveira J. M. Commercial Products for Osteochondral Tissue Repair and Regeneration., Osteochondral Tissue Engineering. Advances in Experimental Medicine and Biology, Vol. 1058, doi:10.1007/978-3-319-76711-6_19, 2018
Abstract(s)The osteochondral tissue represents a complex structure composed of four interconnected structures, namely hyaline cartilage, a thin layer of calcified cartilage, subchondral bone, and cancellous bone. Due to the several difficulties associated with its repair and regeneration, researchers have developed several studies aiming to restore the native tissue, some of which had led to tissue-engineered commercial products. In this sense, this chapter discusses the good manufacturing practices, regulatory medical conditions and challenges on clinical translations that should be fulfilled regarding the safety and efficacy of the new commercialized products. Furthermore, we review the current osteochondral products that are currently being marketed and applied in the clinical setting, emphasizing the advantages and difficulties of each one.
TypeBook part
Publisher version
AccessOpen access
Appears in Collections:3B’s - Capítulos de Livros/Book Chapters

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