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https://hdl.handle.net/1822/33383
Título: | Magnetic cells with surface modified Fe3O4 spherical and rod-shaped nanoparticles for tissue engineering and regenerative medicine applications |
Autor(es): | Gil, Sara Correia, Clara R. Mano, J. F. |
Palavras-chave: | Magnetic nanoparticles Smart responsive systems Targeted cell delivery Three dimensional (3D) cell culture Tissue engineering. |
Data: | Jun-2014 |
Editora: | Wiley |
Revista: | Journal of Tissue Engineering and Regenerative Medicine |
Citação: | Gil S., Correia C. R., Mano J. F. Magnetic cells with surface modified Fe3O4 spherical and rod-shaped nanoparticles for tissue engineering and regenerative medicine applications, Journal of Tissue Engineering and Regenerative Medicine, Vol. 8, pp. 49-50, 2014 |
Resumo(s): | Although magnetic nanoparticles (MNPs) have fueled the field of nanotechnology in the last few years, the application of MNPs in cell-based therapies has seldom been considered. We hypothesized that magnetically labeled cells could be delivered by intravenous injection, and guided to sites of injury within the body, upon magnetic actuation.Moreover, cells could be retained in the damaged site, creating three dimensional tissue constructs that mimic the structure and functional properties of the native tissue. In this work cells were loaded with superparamagnetic Fe3O4 sphere or rod-shaped nanoparticles. The influence of MNPs shape, size, concentration, and time of incubation on cellular internalization was analyzed. Additionally, cell-sheets were successfully generated by magnetic force-based tissue engineering (TE). |
Tipo: | Resumo em ata de conferência |
URI: | https://hdl.handle.net/1822/33383 |
ISSN: | 1932-6254 |
Arbitragem científica: | yes |
Acesso: | Acesso restrito UMinho |
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Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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18081-Abstract -TERMIS EU 2014 - Sara Gil.pdf Acesso restrito! | 291,35 kB | Adobe PDF | Ver/Abrir |