Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/29729
Título: | Interleukin-10: a key cytokine in depression? |
Autor(es): | Roque, Susana Neves, Margarida Correia Mesquita, Ana Raquel Marcelino Palha, Joana Almeida Sousa, Nuno |
Data: | 2009 |
Editora: | Hindawi Publishing Corporation |
Revista: | Cardiovascular Psychiatry and Neurology |
Resumo(s): | An increasing body of evidence implicates proinflammatory cytokines in psychiatric disorders, namely, in depression. Of notice, recent studies showed that anti-inflammatory cytokines, such as IL-10, also modulate depressive-like behavior. In this article, we propose that the anti-inflammatory cytokine IL-10 is a putative link between two of the most widely reported phenomenon observed in depressed patients: the disruption of the hypothalamic-pituitary-adrenal axis and the imbalanced production of cytokines. If so, IL-10 might represent a novel target for antidepressant therapy. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/29729 |
DOI: | 10.1155/2009/187894 |
ISSN: | 2090-0163 |
Versão da editora: | http://www.hindawi.com/journals/cpn/2009/187894/ |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | ICVS - Artigos em revistas internacionais / Papers in international journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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roque s_ cardiovascular psychiatry and neurology 2009 posp.pdf | 810,63 kB | Adobe PDF | Ver/Abrir |