Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/22372
Título: | Computational approaches to standard-compliant biofilm data for reliable analysis and integration |
Autor(es): | Sousa, Ana Margarida Ferreira, Andreia Azevedo, N. F. Pereira, Maria Olívia Lourenço, Anália |
Data: | 2012 |
Editora: | De Gruyter Open |
Revista: | Journal of Integrative Bioinformatics |
Resumo(s): | The study of microorganism consortia, also known as biofilms, is associated to a number of applications in biotechnology, ecotechnology and clinical domains. Nowadays, biofilm studies are heterogeneous and data-intensive, encompassing different levels of analysis. Computational modelling of biofilm studies has become thus a requirement to make sense of these vast and ever-expanding biofilm data volumes. The rationale of the present work is a machine-readable format for representing biofilm studies and supporting biofilm data interchange and data integration. This format is supported by the Biofilm Science Ontology (BSO), the first ontology on biofilms information. The ontology is decomposed into a number of areas of interest, namely: the Experimental Procedure Ontology (EPO) which describes biofilm experimental procedures; the Colony Morphology Ontology (CMO) which characterises morphologically microorganism colonies; and other modules concerning biofilm phenotype, antimicrobial susceptibility and virulence traits. The overall objective behind BSO is to develop semantic resources to capture, represent and share data on biofilms and related experiments in a regularized fashion manner. Furthermore, the present work also introduces a framework in assistance of biofilm data interchange and analysis – BiofOmics (http://biofomics.org) – and a public repository on colony morphology signatures – MorphoCol (http://stardust.deb.uminho.pt/morphocol). |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/22372 |
DOI: | 10.2390/biecoll-jib-2012-203 |
ISSN: | 1613-4516 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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jib-203.pdf | 833,35 kB | Adobe PDF | Ver/Abrir |