Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/15061| Título: | BRCA1, microRNAs and cancer predisposition : challenging the dogma |
| Autor(es): | Almeida, Maria Inês Reis, R. M. Calin, George A. |
| Palavras-chave: | Tumor suppressor gene BRCA1 Single-nucleotide polymorphism (SNP) Functional miRNA interactions |
| Data: | 2011 |
| Editora: | Landes Bioscience |
| Revista: | Cell Cycle |
| Resumo(s): | The importance of SNPs in conveying susceptibility to different kinds of cancer. The study by Pelletier et al. (2011) is particularly vital because it describes new genetic markers in BRCA1 3’UTR noncoding regions that can improve our determination of breast cancer susceptibility. Inclusion of these SNPs in BRCA1 haplotypes that are associated with breast cancer risk may guide future studies of functional miRNA interactions and their cellular consequences. This has the potential to greatly increase our ability to diagnose BRCA1-negative breast cancer at an earlier stage. |
| Tipo: | Editorial em revista |
| URI: | https://hdl.handle.net/1822/15061 |
| DOI: | 10.4161/cc.10.3.14738 |
| ISSN: | 1538-4101 1551-4005 |
| Versão da editora: | http://www.landesbioscience.com/ |
| Arbitragem científica: | yes |
| Acesso: | Acesso aberto |
| Aparece nas coleções: |
Ficheiros deste registo:
| Ficheiro | Descrição | Tamanho | Formato | |
|---|---|---|---|---|
| 2011_Almeida_M01_CellCycle.pdf | Documento principal | 613,84 kB | Adobe PDF | Ver/Abrir |
