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Issue DateTitleAuthor(s)TypeAccess
2013Access: transvesicalLima, Estêvão Augusto Rodrigues de; Correia-Pinto, JorgeBook partRestricted access (Author)
Apr-2016Acute alithiasic cholecystitis and human herpes virus type-6 infection: first caseGomes, Maria Miguel; Antunes, Henedina; Lobo, Ana Luísa, et al.ArticleOpen access
2014Acute pancreatitis in children: a tertiary hospital reportAntunes, Henedina; Nascimento, João; Mesquita, Aurélio, et al.ArticleOpen access
7-Jan-2017Anatomic Thoracoscopic Repair of Esophageal AtresiaFonte, Joana; Barroso, Catarina; Lamas-Pinheiro, Ruben, et al.ArticleOpen access
2017Animal facility videoendoscopic intubation station: tips and tricks from mice to rabbitsMiranda, Alice Augusta Macedo; Pêgo, José M.; Correia-Pinto, JorgeArticleOpen access
Apr-2005Antenatal vitamin A administration attenuates lung hypoplasia by interfering with early instead of late determinants of lung underdevelopment in congenital diaphragmatic herniaBaptista, Maria J.; Rocha, Gustavo Filipe Melo Alves; Pedrosa, Carla, et al.ArticleRestricted access (UMinho)
1-Jul-2016Atrésia Esofágica: Um Desafio desde o Diagnóstico Pré-natal ao Tratamento CirúrgicoTrocado, Vera; Barroso, Catarina; Silva, Cristina Isabel Nogueira, et al.ArticleOpen access
2014Automated image analysis of lung branching morphogenesis from microscopic images of fetal rat explantsRodrigues, Pedro L.; Rodrigues, Nuno F.; Duque, Duarte, et al.ArticleOpen access
2014Automatic modeling of pectus excavatum corrective prosthesis using artificial neural networksRodrigues, Pedro L.; Rodrigues, Nuno F.; Pinho, A. C. Marques de, et al.ArticleOpen access
2013Automatic pre-bended customized prosthesis for pectus excavatum minimal invasive surgery correctionVilaça, João L.; Rodrigues, Pedro; Pinto, Jorge CorreiaArticleOpen access
Jun-2014Automatic prebent customized prosthesis for pectus excavatum minimally invasive surgery correctionVilaça, João L.; Rodrigues, Pedro L.; Soares, Tony Ramos, et al.ArticleRestricted access (Author)
Sep-2006Background Previous morphological studies had produced controversial results with regard to heart development in congenital diaphragmatic hernia (CDH), whereas a few publications investigated cardiac function and myocardial maturation. Myocardium maturation is associated with age-dependent increasing of gene expression of gap junction protein connexin 43 (Cx43), adenosine triphosphatase of the sarcoplasmic reticulum (SERCA2a), as well as switching of myosin heavy chains (MHCs) from β to α isoforms. Our aim was to evaluate myocardium maturity in nitrofen-induced CDH rat model. Methods Fetuses from dated pregnant Sprague-Dawley rats were assigned to 3 experimental groups: control, nitrofen (exposed to nitrofen, without CDH), and CDH (exposed to nitrofen, with CDH). Myocardial samples collected from left ventricle free wall were processed to (i) quantification of messenger RNA (mRNA) of Cx43, SERCA2a, α and β MHC isoforms, as well as β-actin (housekeeping gene); and (ii) separation of MHC isoforms (α and β isoforms) by sodium dodecyl sulfate polyacrylamide gel electrophoresis silver stained. Results We demonstrated that there is no difference in myocardial gene expression of Cx43 (control, 1.0 ± 0.1; nitrofen, 1.1 ± 0.2; CDH, 1.3 ± 0.2) and SERCA2a (control, 1.0 ± 0.1; nitrofen, 0.9 ± 0.1; CDH, 1.0 ± 0.2). Myocardial gene expressions of α and β mRNA of MHC isoforms were slightly decreased both in nitrofen and CDH fetuses when compared with control fetuses, but evaluation of the α-to-β ratios of MHC isoforms at protein level revealed no significant differences between CDH and control (control, 16.9 ± 2.5; CDH, 17.0 ± 2.0). Conclusions Myocardial quantification of Cx43 and SERCA2a mRNA, as well as the expression pattern of MHC isoforms at protein levels, was similar in all studied groups. We predict, therefore, that acute heart failure commonly observed in CDH infants might be attributed predominantly to cardiac overload secondary to severe pulmonary hypertension rather than to myocardial immaturity.Baptista, Maria João; Recamán, Mónica; Rocha, Gustavo Filipe Melo Alves, et al.ArticleRestricted access (UMinho)
2015Benefits of radial distortion correction in arthroscopic surgery : a first experimental study on a knee modelDuarte, Rui M.; Ferreira, Nuno V.; Oliveira, Armando M., et al.ArticleRestricted access (UMinho)
May-2017Biomaterials and bioactive agents in spinal fusionDuarte, Rui M.; Varanda, Pedro; Reis, R. L., et al.ArticleRestricted access (UMinho)
27-Mar-2017Canonical sonic Hedgehog signaling in early lung developmentSilva, Hugo Miguel Fernandes; Correia-Pinto, Jorge; Moura, Rute S.ArticleOpen access
2014Canonical wnt signaling activity in early stages of chick lung developmentMoura, Rute S.; Correia, Eduarda Carvalho; Mota, Paulo O. da, et al.ArticleOpen access
23-Jul-2015Characterization of miRNA processing machinery in the embryonic chick lungMoura, Rute S.; Cunha, Patrícia Vaz; Gonçalves, Carla Silva, et al.ArticleOpen access
2013Collecting system percutaneous access using real-time tracking sensors : first pig model in vivo experienceRodrigues, Pedro L.; Vilaça, João L.; Oliveira, Carlos, et al.ArticleOpen access
Dec-2017Comparative Study of 2D and 3D Optical Imaging Systems: Laparoendoscopic Single-Site Surgery in an Ex Vivo ModelVilaça, Jaime; Pinto, José Pedro; Fernandes, Sandra, et al.ArticleRestricted access (Author)
Oct-2005Congenital diaphragmatic hernia in a patient with tetrasomy 9pHenriques-Coelho, Tiago; Oliva-Teles, Natália; Fonseca-Silva, M. Luz, et al.ArticleOpen access