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TitleComparative study of silicone-hydrogel contact lenses Surfaces before and after wear using atomic force microscopy
Author(s)Lira, Madalena
Santos, Lívia
Azeredo, Joana
Yebra-Pimentel Vilar, Eva
Oliveira, M. Elisabete
KeywordsAtomic force microscopy
Contact lens
Surface analysis
Issue dateMay-2008
PublisherJohn Wiley and Sons
JournalJournal of Biomedical Materials Research Part B: Applied Biomaterials
Citation"Journal of Biomedical Materials Research Part B : Applied Biomaterials". ISSN 1552-4973. 85B:2 (May 2008) 361-367.
Abstract(s)Purpose: The aim of this study was to analyze surface changes of three silicone-hydrogel contact lenses after daily wear. The lenses used in this study were balafilcon A, lotrafilcon B (both surface-treated), and galyfilcon A (non surface-treated). Methods: To understand how and where proteins, lipids, and other contaminants change contact lenses, surface roughness was assessed through Atomic Force Microscopy Tapping ModeTM. Roughness parameters were Mean Surface roughness (Ra), Mean-square-roughness (Rq), and Maximum roughness (Rmax). The surface topography of unworn and worn lenses was also mapped in great detail. Results: Contact lenses roughness parameters exhibited different values before and after wear and the surface appearance also changed. After wear, balafilcon A and galyfilcon A showed a significant increase on surface roughness parameters, being this increase more accentuated to galyfilcon A. In lotrafilcon B materials no significant changes were observed with wear. Conclusions: The present study suggests that surface treatment of silicone-hydrogel contact lenses can play a role in the prevention of a significant increase in roughness, and contribute to the better clinical tolerance of these lenses.
AccessOpen access
Appears in Collections:CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series

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