Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/78382
Título: | Carcinogenicity of cobalt, antimony compounds, and weapons-grade tungsten alloy |
Autor(es): | Karagas, Margaret R. Wang, Amy Dorman, David C. Hall, Amy L. Pi, Jingbo Sergi, Consolato M. Symanski, Elaine Ward, Elizabeth M. Arrandale, Victoria H. Azuma, Kenichi Brambila, Eduardo Calaf, Gloria M. Fritz, Jason M. Fukushima, Shoji Gaitens, Joanna M. Grimsrud, Tom K. Guo, Lei Lynge, Elsebeth Marinho Reis, A. Paula McDiarmid, Melissa A. Middleton, Daniel R. S. Ong, Thomas P. Polya, David A. Quintanilla-Vega, Betzabet Roberts, Georgia K. Santonen, Tiina Sauni, Riitta Silva, Maria J. Wild, Pascal Zhang, Changwen W. Zhang, Qunwei Grosse, Yann Benbrahim-Tallaa, Lamia de Conti, Aline DeBono, Nathan L. El Ghissassi, Fatiha Madia, Federica Reisfeld, Bradley Stayner, Leslie T. Suonio, Eero Viegas, Susana Wedekind, Roland Ahmadi, Shukrullah Mattock, Heidi Gwinn, William M. Schubauer-Berigan, Mary K. |
Data: | 2022 |
Editora: | Elsevier 1 |
Revista: | The Lancet Oncology |
Citação: | Karagas, M. R., Wang, A., Dorman, D. C., Hall, A. L., Pi, J., Sergi, C. M., … Schubauer-Berigan, M. K. (2022, May). Carcinogenicity of cobalt, antimony compounds, and weapons-grade tungsten alloy. The Lancet Oncology. Elsevier BV. http://doi.org/10.1016/s1470-2045(22)00219-4 |
Resumo(s): | [Excerpt] In March, 2022, a Working Group of 31 scientists from 13 countries met remotely at the invitation of the International Agency for Research on Cancer (IARC) to finalise their evaluation of the carcinogenicity of nine agents: cobalt metal (without tungsten carbide or other metal alloys), soluble cobalt(II) salts, cobalt(II) oxide, cobalt(II,III) oxide, cobalt(II) sulfide, other cobalt(II) compounds, trivalent antimony, pentavalent antimony, and weapons-grade tungsten (with nickel and cobalt) alloy. For cobalt metal and the cobalt compounds, particles of all sizes were included in the evaluation. These assessments will be published in Volume 131 of the IARC Monographs.1 Cobalt metal and soluble cobalt(II) salts were classified as “probably carcinogenic to humans” (Group 2A) based on “sufficient” evidence for cancer in experimental animals and “strong” mechanistic evidence in human primary cells. Cobalt(II) oxide and weapons-grade tungsten alloy were classified as “possibly carcinogenic to humans” (Group 2B) based on “sufficient” evidence in experimental animals. Trivalent antimony was classified as “probably carcinogenic to humans” (Group 2A), based on “limited” evidence for cancer in humans, “sufficient” evidence for cancer in experimental animals, and “strong” mechanistic evidence in human primary cells and in experimental systems. Cobalt(II,III) oxide, cobalt(II) sulfide, other cobalt(II) compounds, and pentavalent antimony were each evaluated as “not classifiable as to its carcinogenicity to humans” (Group 3).[...] |
Tipo: | Artigo |
Descrição: | The complete evaluation of the carcinogenicity of cobalt, antimony compounds, and weapons-grade tungsten alloy will be published in Volume 131 of the IARC Monographs. |
URI: | https://hdl.handle.net/1822/78382 |
DOI: | 10.1016/S1470-2045(22)00219-4 |
ISSN: | 1470-2045 |
e-ISSN: | 1474-5488 |
Versão da editora: | https://www.sciencedirect.com/science/article/pii/S1470204522002194 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | CCT - Artigos (Papers)/Papers |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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Karagas et al 2022.pdf | 90,82 kB | Adobe PDF | Ver/Abrir |
Este trabalho está licenciado sob uma Licença Creative Commons