Utilize este identificador para referenciar este registo: http://hdl.handle.net/1822/7467

TítuloAntifungal activity of a novel chromene dimer
Autor(es)Abrunhosa, Luís
Costa, M.
Areias, F.
Venâncio, Armando
Proença, M. Fernanda R. P.
Palavras-chaveChromenes
Aspergillus spp.
Ochratoxin A
Antifungal compounds
DataDez-2007
EditoraSpringer
RevistaJournal of Industrial Microbiology and Biotechnology
Citação"Journal of Industrial Microbiology and Biotechnology". ISSN 1367-5435. 34:12 (2007)787-792.
Resumo(s)The activity on Aspergillus spp. growth and on ochratoxin A production of two novel chromene dimers (3) was evaluated. The results of the bioassays indicate that the chromene dimer 3a inhibited mycelia growth by approximately 50% (EC50) at 140.1 μmol L−1 for A. niger, 384.2 μmol L−1 for A. carbonarius, 69.1 μmol L−1 for A. alliaceus and 559.1 μmol L−1 for A. ochraceus. When applied at concentrations of 2 mmol L−1, 3a totally inhibited the growth of all Aspergillus spp. tested. Furthermore, ochratoxin A production by A. alliaceus was reduced by about 94% with a 200 μmol L−1 solution of this compound. A moderate inhibitory effect was observed for the analogous structure 3b on ochratoxin A production but not in mycelia growth. No inhibition was registered for compounds 2a and 2b, used as synthetic precursors of the dimeric species 3.
Tipoarticle
URIhttp://hdl.handle.net/1822/7467
DOI10.1007/s10295-007-0255-z
ISSN1367-5435
1476-5535
Versão da editorawww.springerlink.com
http://www.springerlink.com/content/?k=Antifungal+activity+of+a+novel+chromene+dimer
Arbitragem científicayes
AcessoopenAccess
Aparece nas coleções:CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series

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