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dc.contributor.authorMendes, B. B.por
dc.contributor.authorGomez-Florit, Manuelpor
dc.contributor.authorOsório, H.por
dc.contributor.authorVilaça, A.por
dc.contributor.authorDomingues, Rui Miguel Andradepor
dc.contributor.authorReis, R. L.por
dc.contributor.authorGomes, Manuela E.por
dc.identifier.citationMendes B. B., Gómez-Florit M., Osório H., Vilaça A., Domingues R. M. A., Reis R. L., Gomes M. E. Cellulose nanocrystals of variable sulfation degrees can sequester specific platelet lysate-derived biomolecules to modulate stem cell response, Chemical Communications, doi:10.1039/D0CC01850C, 2020por
dc.description.abstractThe surface chemistry of cellulose nanocrystals was engineered to show variable sulfation degrees, which was exploited to modulate platelet lysate-derived biomolecule sequestration and presentation. The protein coronas developed on CNC surfaces were characterized and it was demonstrated how they promote different signaling effects on human adipose-derived stem cell behavior.por
dc.description.sponsorshipThe research has received funding from PTDC/NAN-MAT/30595/2017, ERC Grant No. 772817; FCT/MCTES for PD/59/2013 - PD/BD/113807/2015, for ITI Research grant 1306_2018,ROTEIRO/0028/2013, and LISBOA-01-0145-FEDER-022125.por
dc.publisherRoyal Society of Chemistrypor
dc.rightsembargoedAccess (1 Year)por
dc.subjectCellulose nanocrystalspor
dc.subjectPlatelet lysatepor
dc.subjectprotein coronapor
dc.titleCellulose nanocrystals of variable sulfation degrees can sequester specific platelet lysate-derived biomolecules to modulate stem cell responsepor
sdum.journalChemical Communicationspor
Appears in Collections:3B’s - Artigos em revistas/Papers in scientific journals

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