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|Title:||Development of novel magnetoliposomes containing nickel ferrite nanoparticles covered with gold for applications in thermotherapy|
|Author(s):||Rio, Irina S. R.|
Rodrigues, Ana Rita O.
Rodrigues, Carolina P.
Almeida, B. G.
Pereira, A. M.
Araújo, J. P.
Castanheira, Elisabete M. S.
Coutinho, Paulo J. G.
|Publisher:||Multidisciplinary Digital Publishing Institute|
|Citation:||Rio, I.S.R.; Rodrigues, A.R.O.; Rodrigues, C.P.; Almeida, B.G.; Pires, A.; Pereira, A.M.; Araújo, J.P.; Castanheira, E.M.S.; Coutinho, P.J.G. Development of Novel Magnetoliposomes Containing Nickel Ferrite Nanoparticles Covered with Gold for Applications in Thermotherapy. Materials 2020, 13, 815.|
|Abstract(s):||Multifunctional nanosystems combining magnetic and plasmonic properties are a promising approach for cancer therapy, allowing magnetic guidance and a local temperature increase. This capability can provide a triggered drug release and synergistic cytotoxic effect in cancer cells. In this work, nickel ferrite/gold nanoparticles were developed, including nickel ferrite magnetic nanoparticles decorated with plasmonic gold nanoparticles and core/shell nanostructures (with a nickel ferrite core and a gold shell). These nanoparticles were covered with a surfactant/lipid bilayer, originating liposome-like structures with diameters below 160 nm. The heating capacity of these systems, upon excitation with light above 600 nm wavelength, was assessed through the emission quenching of rhodamine B located in the lipid layer. The developed nanosystems show promising results for future applications in thermotherapy.|
|Appears in Collections:||PHYSICS OF QUANTUM MATERIALS AND BIONANOSTRUCTURES (2018 - ...)|
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