Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/64495

TitleDevelopment of novel magnetoliposomes containing nickel ferrite nanoparticles covered with gold for applications in thermotherapy
Author(s)Rio, Irina S. R.
Rodrigues, Ana Rita O.
Rodrigues, Carolina P.
Almeida, B. G.
Pires, A.
Pereira, A. M.
Araújo, J. P.
Castanheira, Elisabete M. S.
Coutinho, Paulo J. G.
Keywordsmagnetic
plasmonic nanoparticles
nickel ferrite
gold
magnetoliposomes
thermotherapy
Magnetic/plasmonic nanoparticles
Issue date11-Feb-2020
PublisherMultidisciplinary Digital Publishing Institute
JournalMaterials
CitationRio, I.S.R.; Rodrigues, A.R.O.; Rodrigues, C.P.; Almeida, B.G.; Pires, A.; Pereira, A.M.; Araújo, J.P.; Castanheira, E.M.S.; Coutinho, P.J.G. Development of Novel Magnetoliposomes Containing Nickel Ferrite Nanoparticles Covered with Gold for Applications in Thermotherapy. Materials 2020, 13, 815.
Abstract(s)Multifunctional nanosystems combining magnetic and plasmonic properties are a promising approach for cancer therapy, allowing magnetic guidance and a local temperature increase. This capability can provide a triggered drug release and synergistic cytotoxic effect in cancer cells. In this work, nickel ferrite/gold nanoparticles were developed, including nickel ferrite magnetic nanoparticles decorated with plasmonic gold nanoparticles and core/shell nanostructures (with a nickel ferrite core and a gold shell). These nanoparticles were covered with a surfactant/lipid bilayer, originating liposome-like structures with diameters below 160 nm. The heating capacity of these systems, upon excitation with light above 600 nm wavelength, was assessed through the emission quenching of rhodamine B located in the lipid layer. The developed nanosystems show promising results for future applications in thermotherapy.
TypeArticle
URIhttp://hdl.handle.net/1822/64495
DOI10.3390/ma13040815
e-ISSN1996-1944
Publisher versionhttps://www.mdpi.com/1996-1944/13/4/815
Peer-Reviewedyes
AccessOpen access
Appears in Collections:PHYSICS OF QUANTUM MATERIALS AND BIONANOSTRUCTURES (2018 - ...)

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