Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/63673

TitleNew method to produce poly(vinyl alcohol)/cellulose acetate films with improved antibacterial action
Author(s)Felgueiras, Helena Prado
Teixeira, Marta Albertina
Tavares, Tânia Daniela Eugénio
Amorim, M. T. Pessoa de
KeywordsBiodegradable polymers
Solvent casting
Phase-inversion
Antimicrobial peptides
Antibacterial activity
Wound-healing applications
Issue date2020
PublisherElsevier
JournalMaterials Today: Proceedings
Abstract(s)New alternatives to the conventional wound dressings are being engineered. Here, we propose the processing of two biodegradable polymers, poly(vinyl alcohol) (PVA) and cellulose acetate (CA), in the form of films via a new method that combines principles of solvent casting and phase-inversion. Highly flexible and mechanically resistant films were obtained. PVA/CA films were then treated with the antibiotic vancomycin via two methods, blending and physisorption (via dopamine). Immobilization of vancomycin was proven efficient in promoting the films' antibacterial action against Staphylococcus epidermidis bacteria. Data demonstrates the potentialities of PVA/CA films for prospective wound healing applications.
TypeConference paper
URIhttp://hdl.handle.net/1822/63673
DOI10.1016/j.matpr.2019.12.100
Publisher versionhttps://www.sciencedirect.com/science/article/pii/S2214785319341112
Peer-Reviewedyes
AccessOpen access
Appears in Collections:DET/2C2T - Comunicações em congressos internacionais com arbitragem científica

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