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https://hdl.handle.net/1822/63517
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Campo DC | Valor | Idioma |
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dc.contributor.author | Barros, Lillian | por |
dc.contributor.author | Pereira, Eliana | por |
dc.contributor.author | Calhelha, Ricardo C. | por |
dc.contributor.author | Dueñas, Montserrat | por |
dc.contributor.author | Carvalho, Ana Maria | por |
dc.contributor.author | Santos-Buelga, Celestino | por |
dc.contributor.author | Ferreira, Isabel C. F. R. | por |
dc.date.accessioned | 2020-01-30T15:51:35Z | - |
dc.date.available | 2020-01-30T15:51:35Z | - |
dc.date.issued | 2013 | - |
dc.identifier.citation | Barros, Lillian; Pereira, Eliana; Calhelha, Ricardo C.; Dueñas, Montserrat; Carvalho, Ana Maria; Santos-Buelga, Celestino; Ferrreira, Isabel C.F.R. (2013). Bioactivity and chemical characterization in hydrophilic and lipophilic compounds of Chenopodium ambrosioides L. Journal of Functional Foods. ISSN 1756-4646. 5:4, p. 1732–1740. | por |
dc.identifier.issn | 1756-4646 | por |
dc.identifier.uri | https://hdl.handle.net/1822/63517 | - |
dc.description.abstract | The bioactive properties (antioxidant and antitumour activities, and hepatotoxicity) of the infusion and methanolic extracts of Chenopodium ambrosioides L., a plant commonly used in Portuguese folk medicine, were compared. The chemical composition in hydrophilic (sugars, organic acids and phenolic compounds) and lipophilic (fatty acids and tocopherols) fractions were determined. In general, the infusion revealed higher antioxidant activity, while the methanolic extract was the only one showing antitumour effects against colon, cervical and hepatocellular carcinoma cell lines. No toxicity in non-tumour cells was observed either for the infusion or the extract. The studied plant proved to be a good source of natural antioxidants and other bioactive compounds, which may have industrial use. As far as we know, this is the first detailed chemical characterization and bioactivity evaluation of C. ambrosioides methanolic extract and infusion. | por |
dc.description.sponsorship | The authors are grateful to Fundacao para a Ciencia e a Tecnologia (FCT, Portugal) for financial support to CIMO (strategic project PEst-OE/AGR/UI0690/2011). R.C. Calhelha and L. Barros also thank to FCT, POPH-QREN and FSE for their grants (SFRH/BPD/BPD/68344/2010 and SFRH/BPD/4609/2008, respectively). The GIP-USAL is financially supported by the Spanish Government through the Consolider-Ingenio 2010 Programme (FUN-C-FOOD, CSD2007-00063). M. Duenas thanks to the Programa Ramon y Cajal for a contract. | por |
dc.language.iso | eng | por |
dc.publisher | Elsevier Science BV | por |
dc.relation | PEst-OE/AGR/UI0690/2011 | por |
dc.relation | SFRH/BPD/BPD/68344/2010 | por |
dc.relation | SFRH/BPD/4609/2008 | por |
dc.rights | openAccess | por |
dc.subject | Chenopodium ambrosioides L. | por |
dc.subject | Antioxidant activity | por |
dc.subject | Antitumour activity | por |
dc.subject | Chemical compounds | por |
dc.title | Bioactivity and chemical characterization in hydrophilic and lipophilic compounds of Chenopodium ambrosioides L | por |
dc.type | article | por |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | http://www.sciencedirect.com/science/journal/17564646 | por |
oaire.citationStartPage | 1732 | por |
oaire.citationEndPage | 1740 | por |
oaire.citationIssue | 4 | por |
oaire.citationVolume | 5 | por |
dc.identifier.doi | 10.1016/j.jff.2013.07.019 | por |
dc.subject.wos | Science & Technology | por |
sdum.journal | Journal of Functional Foods | por |
oaire.version | AM | por |
Aparece nas coleções: | CDQuim - Artigos (Papers) |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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Artigo C. ambrosioides_JFF_Revised.pdf | 506,13 kB | Adobe PDF | Ver/Abrir |