Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/63348

TitleAquatic insects and Mycobacterium ulcerans: an association relevant to Buruli ulcer control?
Author(s)Silva, Manuel T
Portaels, Françoise
Pedrosa, Jorge
KeywordsAnimals
Antigens
Disease Vectors
Humans
Insecta
Mycobacterium Infections, Nontuberculous
Mycobacterium ulcerans
Saliva
Skin Ulcer
Vaccination
Issue dateFeb-2007
PublisherPublic Library of Science (PLOS)
JournalPLoS Medicine
CitationSilva MT, Portaels F, Pedrosa J (2007) Aquatic Insects and Mycobacterium ulcerans: An Association Relevant to Buruli Ulcer Control? PLoS Med 4(2): e63. https://doi.org/10.1371/journal.pmed.0040063
Abstract(s)[Excerpt] Mycobacterium ulcerans infection, which can cause Buruli ulcer, is the third most common human mycobacteriosis worldwide, after tuberculosis and leprosy. Buruli ulcer occurs predominantly in humid tropical areas of Asia, Latin America, and, mainly, Africa, where the incidence has been increasing, surpassing tuberculosis and leprosy in some regions [1].Buruli ulcer is a devastating, necrotizing, “skin-eating” disease of the poor, sometimes producing massive, disfi guring ulcers, with a huge social impact [1,2]. Furthermore, both Buruli ulcer and its pathogen have high scientifi c interest, with unique, enigmatic, and controversial features [1–4]. However, research on Buruli ulcer has been limited, although interest has grown since 1998, when the World Health Organization established the Global Buruli Ulcer Initiative, and in 2004 called for urgent action to control the disease and to increase research. There is no vaccine against Buruli ulcer and treatment remains diffi cult [1,2,5]. A detailed description of M. ulceransinfection, including its clinical aspects, is available at http:⁄⁄www.afi p.org/Departments/infectious/bu/. [...]
TypeJournal editorial
URIhttp://hdl.handle.net/1822/63348
DOI10.1371/journal.pmed.0040063
ISSN1549-1277
Peer-Reviewedyes
AccessOpen access
Appears in Collections:ICVS - Artigos em Revistas Internacionais com Referee

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