The effect of culture media on in vitro growth and biofilm formation of Bacterial vaginosis (BV)-associated pathogens

Abstract

Background: Bacterial vaginosis (BV) is an important vaginal bacterial disorder worldwide, being characterized by a change in the vaginal microbial composition from a health-associated microbiota to a dense polymicrobial biofilm. Although this biofilm plays an important role in BV progress and recurrence, very little information exists regarding its in vitro formation. The current study aimed to investigate the influence of different culture media on the planktonic growth and biofilm formation ability of BV- associated microorganisms, namely Gardnerella sp., Atopobium vaginae, Lactobacillus iners, Mobiluncus curtisii, Peptostreptococcus anaerobius and Prevotella bivia.