Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/62448
Título: | Stereoselective synthesis of 5-substituted hexahydropyrroquinolines-2,3-diol from functionalized tetrahydroquinolines |
Autor(es): | Drogalin, Artem Alves, Maria José Castro, Tarsila Gabriel |
Data: | 20-Nov-2019 |
Citação: | Drogalin, Artem; Alves, Maria José; Castro, T., Stereoselective synthesis of 5-substituted hexahydropyrroquinolines-2,3-diol from functionalized tetrahydroquinolines. XXV Encontro Galego-Português de Química. No. QO25, Santiago de Compostela, Spain, Nov 20-22, 358, 2019. |
Resumo(s): | [Excerpt] 1,2,3,4-Tetrahydroquinolines (THQ) had shown diverse biological activities such as antiarrhythmic, cardiovascular, anticancer and immunosuppressor agents [1]. In this work tetrahydroquinolines 2 were synthesized by Povarov’s reaction [3] from Schiff base 1, being subsequently cyclized to hexahydropyrroquinolines-2,3-diol (HHPQ) 3a-c using trivial reagents. Some new THQ bearing a trihydroxypropyl arm have already been synthetized. [...] |
Tipo: | Resumo em ata de conferência |
URI: | https://hdl.handle.net/1822/62448 |
Versão da editora: | https://www.encontrogalegoportugues.org/ |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
---|---|---|---|---|
document_52223_1.pdf | 313,65 kB | Adobe PDF | Ver/Abrir | |
document_52223_2.pdf | 305,96 kB | Adobe PDF | Ver/Abrir |