Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/62317

TitleA multidimensional concept for mercury neuronal and sensory toxicity in fish - From toxicokinetics and biochemistry to morphometry and behavior
Author(s)Pereira, Patrícia
Korbas, Malgorzata
Pereira, Vitória
Cappello, Tiziana
Maisano, Maria
Canário, João
Almeida, Armando
Pacheco, Mário
KeywordsAquatic toxicology
Brain
Fish
Mercury
Neurotoxicity
Sensory organs
Issue dateDec-2019
PublisherElsevier
JournalBiochimica et Biophysica Acta (BBA). General Subjects
Abstract(s)Neuronal and sensory toxicity of mercury (Hg) compounds has been largely investigated in humans/mammals with a focus on public health, while research in fish is less prolific and dispersed by different species. Well-established premises for mammals have been governing fish research, but some contradictory findings suggest that knowledge translation between these animal groups needs prudence [e.g. the relative higher neurotoxicity of methylmercury (MeHg) vs. inorganic Hg (iHg)]. Biochemical/physiological differences between the groups (e.g. higher brain regeneration in fish) may determine distinct patterns. This review undertakes the challenge of identifying sensitive cellular targets, Hg-driven biochemical/physiological vulnerabilities in fish, while discriminating specificities for Hg forms.
TypeArticle
URIhttp://hdl.handle.net/1822/62317
DOI10.1016/j.bbagen.2019.01.020
ISSN0304-4165
Peer-Reviewedyes
AccessRestricted access (UMinho)
Appears in Collections:ICVS - Artigos em Revistas Internacionais com Referee

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