Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/61848
Título: | Exosome-like nanoparticles: a new type of nanocarrier |
Autor(es): | Fernandes, Mário Lopes, Ivo Teixeira, J. A. Botelho, C. M. Gomes, Andreia C |
Palavras-chave: | Nanoparticles Exosomes Exosome-like nanoparticles Nanomedicine Drug delivery Extracellular vesicles Exosome mimetics |
Data: | 2020 |
Editora: | Bentham Science Publishers |
Revista: | Current Medicinal Chemistry |
Resumo(s): | Nanoparticles are one of the most used systems for imaging or therapeutic drug delivery. Exosomes are nanovesicular carriers that transport cargo for intercellular communication. These nanovesicles are linked to the pathology of some major diseases, in some cases with a central role in their progression. The use of these carriers to transport therapeutic drugs is a recent and promising approach to treat diseases such as cancer and Alzheimer disease. The physiological production of these structures is limited impairing its collection and subsequent purification. These drawbacks inspired the search for mimetic alternatives. The collection of exosome-like nanoparticles from plants can be a good alternative, since they are easier to extract and do not have the drawbacks of those produced in animal cells. Both natural and synthetic exosome-like nanoparticles, produced from serial extrusion of cells or by bottom up synthesis, are currently some of the most promising, biocompatible, high efficiency systems for drug delivery. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/61848 |
DOI: | 10.2174/0929867326666190129142604 |
ISSN: | 0929-8673 |
e-ISSN: | 1875-533X |
Arbitragem científica: | yes |
Acesso: | Acesso restrito autor |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series CBMA - Artigos/Papers DBio - Artigos/Papers |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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Gomes-MS.pdf Acesso restrito! | 528,24 kB | Adobe PDF | Ver/Abrir |
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