Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/61661

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dc.contributor.authorSantos, Diana I.por
dc.contributor.authorSaraiva, Jorge Manuel Alexandrepor
dc.contributor.authorVicente, A. A.por
dc.contributor.authorMoldão-Martins, Margaridapor
dc.date.accessioned2019-10-08T10:49:39Z-
dc.date.issued2019-
dc.identifier.citationSantos, Diana I.; Saraiva, Jorge M. A.; Vicente, António A.; Moldão-Martins, Margarida, 2 - Methods for determining bioavailability and bioaccessibility of bioactive compounds and nutrients. In Francisco J. Barba, Jorge Manuel Alexandre Saraiva, Giancarlo Cravotto, José M. Lorenzo, Innovative Thermal and Non-Thermal Processing, Bioaccessibility and Bioavailability of Nutrients and Bioactive Compounds, Woodhead Publishing, 2019. ISBN: 978-0-12-814174-8, 23-54por
dc.identifier.isbn978-0-12-814174-8por
dc.identifier.urihttp://hdl.handle.net/1822/61661-
dc.description.abstractThe health advantages of bioactive compounds and nutrients are based on intake levels and the amount of these compounds that become bioavailable and bioaccessible. The determination of bioactive compounds directly in food is not sufficient to evaluate the bioavailability and bioaccessibility and consequently their effects in vivo, since the compounds reaching the blood system result from a complex digestion process. Bioavailability is assessed by in vivo methodologies using gastrointestinal digestion, absorption, metabolism, tissue distribution, and bioactivity. In vitro methodologies allow for determining the bioaccessibility of the bioactive compounds and nutrients through liberation from the food matrix, simulation of gastrointestinal digestion, and assimilation by intestinal epithelium. This chapter presents the similarities and differences between the distinct techniques used to quantify bioavailability and bioaccessibility, as well as a brief description of the methodologies applied to determine different bioactive compounds and nutrients.por
dc.description.sponsorshipThe first author acknowledges the financial support from Fundação para a Ciência e a Tecnologia (FCT), Portugal, through doctoral fellowship (SFRH/BD/109124/2015). This work was supported by the national funding of FCT, and where applicable co-financed by the FEDER, within the PT2020 Partnership Agreement, under the scope of the strategic funding to the research units LEAF (UID/AGR/04129/2013), QOPNA (UID/QUI/00062/2013), and CEB (UID/ BIO/04469/2013).por
dc.language.isoengpor
dc.publisherWoodhead Publishingpor
dc.relationinfo:eu-repo/grantAgreement/FCT/5876/147340/PTpor
dc.relationinfo:eu-repo/grantAgreement/FCT/5876/147415/PTpor
dc.relationinfo:eu-repo/grantAgreement/FCT/5876/147337/PTpor
dc.rightsrestrictedAccesspor
dc.subjectBioactive compoundspor
dc.subjectNutrientspor
dc.subjectBioavailabilitypor
dc.subjectBioaccessibilitypor
dc.subjectIn vitro and in vivo methodologiespor
dc.title2 - Methods for determining bioavailability and bioaccessibility of bioactive compounds and nutrientspor
dc.title.alternativeMethods for determining bioavailability and bioaccessibility of bioactive compounds and nutrientspor
dc.typebookPartpor
dc.peerreviewedyes-
dc.relation.publisherversionhttps://www.sciencedirect.com/book/9780128141748/innovative-thermal-and-non-thermal-processing-bioaccessibility-and-bioavailability-of-nutrients-and-bioactive-compoundspor
dc.commentsCEB51814por
oaire.citationStartPage23por
oaire.citationEndPage54por
dc.date.updated2019-09-28T12:36:27Z-
dc.identifier.doi10.1016/B978-0-12-814174-8.00002-0por
dc.date.embargo10000-01-01-
dc.identifier.esbn978-0-12-814175-5por
dc.description.publicationversioninfo:eu-repo/semantics/publishedVersion-
sdum.bookTitleInnovative thermal and non-thermal processing, bioaccessibility and bioavailability of nutrients and bioactive compoundspor
oaire.citationEdition1por
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