Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/6062

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dc.contributor.authorHenriques, Mariana-
dc.contributor.authorMartins, Margarida Isabel Barros Coelho-
dc.contributor.authorAzeredo, Joana-
dc.contributor.authorOliveira, Rosário-
dc.date.accessioned2007-01-23T12:17:24Z-
dc.date.available2007-01-23T12:17:24Z-
dc.date.issued2007-02-
dc.identifier.citation"Letters in applied microbiology". ISSN 0266-8254. 44:2 (Febr. 2007) 199-205.eng
dc.identifier.issn0266-8254eng
dc.identifier.urihttp://hdl.handle.net/1822/6062-
dc.description.abstractCell–cell signalling in Candida albicans is a known phenomenon and farnesol was identified as a quorum sensing molecule determining the yeast morphology. The aim of this work was to verify if farnesol had a similar effect on Candida dubliniensis, highlighting the effect of farnesol on Candida spp. morphogenesis. Methods and Results: Two different strains of C. dubliniensis and one of C. albicans were grown both in RPMI 1640 and in serum in the presence of absence of farnesol. At 150 μmol l -1 farnesol the growth rate of both Candida species was not affected. On the contrary, farnesol inhibited hyphae and pseudohyphae formation in C. dubliniensis. Conclusion: Farnesol seems to mediate cell morphology in both Candida species. Significance and Impact of the Study: The effect of farnesol on C. dubliniensis morphology was not reported previously.eng
dc.description.sponsorshipFundação para a Ciência e a Tecnologia (FCT)por
dc.language.isoengeng
dc.publisherBlackwell Publishingeng
dc.rightsopenAccesseng
dc.subjectCandida albicanseng
dc.subjectCandida dubliniensiseng
dc.subjectFarnesoleng
dc.subjectHyphaeeng
dc.subjectMorphology alterationeng
dc.subjectPseudohyphaeeng
dc.titleEffect of farnesol on Candida dubliniensis morphogenesiseng
dc.typearticlepor
dc.peerreviewedyeseng
sdum.number2eng
sdum.pagination199–205eng
sdum.publicationstatuspublishedeng
sdum.volume44eng
oaire.citationStartPage199por
oaire.citationEndPage205por
oaire.citationIssue2por
oaire.citationVolume44por
dc.identifier.doi10.1111/j.1472-765X.2006.02044.xpor
dc.identifier.pmid17257261por
dc.subject.wosScience & Technologypor
sdum.journalLetters in Applied Microbiologypor
Appears in Collections:CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series

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