Please use this identifier to cite or link to this item:

TitleEffect of farnesol on Candida dubliniensis morphogenesis
Author(s)Henriques, Mariana
Martins, Margarida Isabel Barros Coelho
Azeredo, Joana
Oliveira, Rosário
KeywordsCandida albicans
Candida dubliniensis
Morphology alteration
Issue dateFeb-2007
PublisherBlackwell Publishing
JournalLetters in Applied Microbiology
Citation"Letters in applied microbiology". ISSN 0266-8254. 44:2 (Febr. 2007) 199-205.
Abstract(s)Cell–cell signalling in Candida albicans is a known phenomenon and farnesol was identified as a quorum sensing molecule determining the yeast morphology. The aim of this work was to verify if farnesol had a similar effect on Candida dubliniensis, highlighting the effect of farnesol on Candida spp. morphogenesis. Methods and Results: Two different strains of C. dubliniensis and one of C. albicans were grown both in RPMI 1640 and in serum in the presence of absence of farnesol. At 150 μmol l -1 farnesol the growth rate of both Candida species was not affected. On the contrary, farnesol inhibited hyphae and pseudohyphae formation in C. dubliniensis. Conclusion: Farnesol seems to mediate cell morphology in both Candida species. Significance and Impact of the Study: The effect of farnesol on C. dubliniensis morphology was not reported previously.
AccessOpen access
Appears in Collections:CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series

Files in This Item:
File Description SizeFormat 
Henriques_LAM[1].pdf611,37 kBAdobe PDFView/Open

Partilhe no FacebookPartilhe no TwitterPartilhe no DeliciousPartilhe no LinkedInPartilhe no DiggAdicionar ao Google BookmarksPartilhe no MySpacePartilhe no Orkut
Exporte no formato BibTex mendeley Exporte no formato Endnote Adicione ao seu ORCID