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http://hdl.handle.net/1822/60504
Title: | Micro-CT - A Digital 3D Microstructural Voyage into Scaffolds: A Systematic Review of the Reported Methods and Results |
Author(s): | Cengiz, I. F. Oliveira, Joaquim M. Reis, R. L. |
Keywords: | Microstructure Mineral density scaffolds Systematic review Tissue engineering |
Issue date: | Sep-2018 |
Journal: | Biomaterials Research |
Citation: | Cengiz I. F., Oliveira J. M., Reis R. L. Micro-CT - A Digital 3D Microstructural Voyage into Scaffolds: A Systematic Review of the Reported Methods and Results, Biomaterials Research , doi:10.1186/s40824-018-0136-8, 2018 |
Abstract(s): | Background: Cell behavior is the key to tissue regeneration. Given the fact that most of the cells used in tissue engineering are anchorage-dependent, their behavior including adhesion, growth, migration, matrix synthesis, and differentiation is related to the design of the scaffolds. Thus, characterization of the scaffolds is highly required. Micro-computed tomography (micro-CT) provides a powerful platform to analyze, visualize, and explore any portion of interest in the scaffold in a 3D fashion without cutting or destroying it with the benefit of almost no sample preparation need. Main body: This review highlights the relationship between the scaffold microstructure and cell behavior, and provides the basics of the micro-CT method. In this work, we also analyzed the original papers that were published in 2016 through a systematic search to address the need for specific improvements in the methods section of the papers including the amount of provided information from the obtained results. |
Type: | Article |
URI: | http://hdl.handle.net/1822/60504 |
DOI: | 10.1186/s40824-018-0136-8 |
ISSN: | 2055-7124 |
Publisher version: | 10.1186/s40824-018-0136-8 |
Peer-Reviewed: | yes |
Access: | Open access |
Appears in Collections: | 3B’s - Artigos em revistas/Papers in scientific journals |
Files in This Item:
File | Description | Size | Format | |
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19858-Micro-CT – a digital 3D microstructural voyage into scaffolds_a systematic review of the reported methods and results.pdf | 1,43 MB | Adobe PDF | View/Open |
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