Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/60046

TitleA semi-automated microfluidic platform for real-time tracking of cancer cells and investigation of nanoparticles cellular uptake
Author(s)Carvalho, M. R.
Maia, F. Raquel
Silva-Correia, Joana
Costa, B. M.
Reis, R. L.
Oliveira, Joaquim M.
KeywordsCancer
Microfluidics
Nanoparticles
Issue date25-Jan-2017
CitationCarvalho M. R., Maia F. R., Silva-Correia J., Costa B. M., Reis R. L., and Oliveira J. M., "A semi-automated microfluidic platform for real-time tracking of cancer cells and investigation of nanoparticles cellular uptake", Society for Biomaterials 2017, 2017.
Abstract(s)Statement of Purpose: Circulating tumor cells (CTCs) have been highly studied due to its implication in cancer dissemination and metastases. Thus, an approach capable of hindering their dissemination could help prevent 90% of cancer deaths (1). Labeled nanoparticles (NPs) have been proposed to track cells and monitor the efficiency of any new cancer therapy in real time. The association of NPs to a microfluidic device, such as Vena8 biochips (Figure 2), allows the accomplishment of functions in vitro that are not easily imaginable in conventional biological analysis (e.g., simulation of physiological flow and shear stress). This novel approach may expedite therapies’ validation and its successful translation into clinics. In this study, we aim to develop an improved platform composed of labeled dendrimer nanoparticles and a microfluidic device for realtime monitoring of cancer cells fate
TypeconferenceAbstract
URIhttp://hdl.handle.net/1822/60046
ISSN1473-2262
Peer-Reviewedyes
AccessopenAccess
Appears in Collections:3B’s - Resumos em livros de atas de conferências - indexados no ISI Web of Science

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