Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/58938

TitleTandem palladium-catalyzed borylation and Suzuki coupling (BSC) to thienocarbazole precursors
Author(s)Ferreira, Isabel C. F. R.
Queiroz, Maria João R. P.
Kirsch, Gilbert
Keywordspalladium
borylation
Suzuki coupling
2-methyl-2 '-nitro biaryls
benzo[b]thiophenes
Issue date2003
PublisherElsevier Ltd
JournalTetrahedron Letters
Abstract(s)Substituted 2-methyl-2 -nitro diaryl compounds in the benzo[b]thiophene series were prepared by palladium-catalyzed, two-step, one-pot borylation/Suzuki coupling (BSC) reaction in good to high yields. The borylation reaction was performed on methylated 6-bromobenzo[b]thiophenes using pinacolborane and was followed by in situ Suzuki coupling with substituted (CF3, OMe) 2-bromonitrobenzenes. The compounds obtained were cyclized to the corresponding ring A substituted thienocarbazoles which can have biological activity or/and be used as biomarkers due to their fluorescence properties and possible DNA intercalation.
TypeArticle
URIhttp://hdl.handle.net/1822/58938
DOI10.1016/S0040-4039(03)00952-3
ISSN0040-4039
Peer-Reviewedyes
AccessOpen access
Appears in Collections:CDQuim - Artigos (Papers)

Files in This Item:
File Description SizeFormat 
TETLET03.pdf119,38 kBAdobe PDFView/Open

Partilhe no FacebookPartilhe no TwitterPartilhe no DeliciousPartilhe no LinkedInPartilhe no DiggAdicionar ao Google BookmarksPartilhe no MySpacePartilhe no Orkut
Exporte no formato BibTex mendeley Exporte no formato Endnote Adicione ao seu ORCID