Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/58770
Título: | Nanotechnology in peripheral nerve repair and reconstruction |
Autor(es): | Carvalho, C. R. Silva-Correia, J. Oliveira, Joaquim M. Reis, R. L. |
Palavras-chave: | Nanomedicine nanotechnology Peripheral Nerve Regeneration Carbon nanomaterials Nanoparticles Nanofibers Nanoimaging Repair Tubular conduits |
Data: | Jan-2019 |
Editora: | Elsevier |
Revista: | Advanced Drug Delivery Reviews |
Citação: | Carvalho C. R., Silva-Correia J., Oliveira J. M., Reis R. L. Nanotechnology in Peripheral Nerve Repair and Reconstruction, Advanced Drug Delivery Reviews, doi:10.1016/j.addr.2019.01.006, 2019 |
Resumo(s): | The recent progress in biomaterials science and development of tubular conduits (TCs) still fails in solving the current challenges in the treatment of peripheral nerve injuries (PNIs), in particular when disease-related and long-gap defects need to be addressed. Nanotechnology-based therapies that seemed unreachable in the past are now being considered for the repair and reconstruction of PNIs, having the power to deliver bioactive molecules in a controlled manner, to tune cellular behavior, and ultimately guide tissue regeneration in an effective manner. It also offers opportunities in the imaging field, with a degree of precision never achieved before, which is useful for diagnosis, surgery and in the patientâ s follow-up. Nanotechnology approaches applied in PNI regeneration and theranostics, emphasizing the ones that are moving from the lab bench to the clinics, are herein overviewed. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/58770 |
DOI: | 10.1016/j.addr.2019.01.006 |
ISSN: | 0169-409X |
e-ISSN: | 1872-8294 |
Versão da editora: | https://www.sciencedirect.com/science/article/pii/S0169409X19300092 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | 3B’s - Artigos em revistas/Papers in scientific journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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19715-FINAL PDF REVIEW.pdf | 2,43 MB | Adobe PDF | Ver/Abrir |