Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/58733

TitleIn vitro and in vivo assessment of magnetically actuated biomaterials for tendon regeneration
Author(s)Santos, L. J.
Silva, M.
Gonçalves, A. I.
Pesqueira, T.
Rodrigues, M. T.
Reis, R. L.
Gomes, M. E.
Keywordsmedical application
regenerative medicine
stimuli-response
Issue dateMar-2016
CitationSantos L. J., Silva M., Gonçalves A. I., Pesqueira T., Rodrigues M. T., Reis R. L., Gomes M. E. In vitro and in vivo assessment of magnetically actuated biomaterials for tendon regeneration, Front. Bioeng. Biotechnol., doi:10.3389/conf.FBIOE.2016.01.01620, 2016
Abstract(s)Tendon regeneration can be undermined by the formation of fibrous adhesions (scar tissue) between the healing tendon and the surrounding tissues. Scarring is associated with the recruitment of inflammatory cells such as macrophages and mast cells[1]. To tackle this issue we advocate the implementation of postoperative rehabilitation programmes to control inflammation levels and scarring, ensuring this way better clinical outcomes. In this study we propose the insertion of a magnetic responsive biomaterial between the healing tendon and the surrounding tissues. We hypothesise this material in combination with a magnetic field will modulate inflammation and reduce fibrous adhesion. Here we present the results from the first stage of our study, where magnetic biomaterials were tested subcutaneously to evaluate the inflammatory response and the ability of this material to control the presence of fibrous tissue.
TypeAbstract
URIhttp://hdl.handle.net/1822/58733
DOI10.3389/conf.FBIOE.2016.01.01620
ISSN2296-4185
Publisher versionhttps://www.frontiersin.org/10.3389/conf.FBIOE.2016.01.01620/event_abstract
Peer-Reviewedyes
AccessOpen access
Appears in Collections:3B’s - Resumos em livros de atas de conferências - indexados no ISI Web of Science

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