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TitlePlasmodium falciparum Plasmepsin 2 Duplications, West Africa
Author(s)Inoue, Juliana
Silva, Miguel
Fofana, Bakary
Sanogo, Kassim
Mårtensson, Andreas
Sagara, Issaka
Björkman, Anders
Veiga, Maria Isabel
Ferreira, Pedro Eduardo
Djimde, Abdoulaye
Gil, José Pedro
Issue date2018
PublisherCenters for Disease Control and Prevention (CDC)
JournalEmerging Infectious Diseases
Abstract(s)Dihydroartemisinin/piperaquine (DHA/PPQ) is increasingly deployed as antimalaria drug in Africa. We report the detection in Mali of Plasmodium falciparum infections carrying plasmepsin 2 duplications (associated with piperaquine resistance) in 7/65 recurrent infections within 2 months after DHA/PPQ treatment. These findings raise concerns about the long-term efficacy of DHA/PPQ treatment in Africa.
TypeLetter to the editor
AccessOpen access
Appears in Collections:ICVS - Artigos em Revistas Internacionais com Referee

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