Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/57878

TitleGeneration of an integration-free induced pluripotent stem cell line (CSC-43) from a patient with sporadic Parkinson's disease
Author(s)Marote, Ana
Pomeshchik, Yuriy
Goldwurm, Stefano
Collin, Anna
Lamas, Nuno J.
Pinto, Luísa
Salgado, A. J.
Roybon, Laurent
KeywordsAdult
Cell Differentiation
Cell Line
Cellular Reprogramming
Humans
Induced Pluripotent Stem Cells
Kruppel-Like Transcription Factors
Male
Octamer Transcription Factor-3
Parkinson Disease
Proto-Oncogene Proteins c-myc
SOXB1 Transcription Factors
Issue date2018
PublisherElsevier
JournalStem Cell Research
CitationMarote, A., Pomeshchik, Y., Goldwurm, et. al. (2018). Generation of an integration-free induced pluripotent stem cell line (CSC-43) from a patient with sporadic Parkinson's disease. Stem cell research, 27, 82-85
Abstract(s)An induced pluripotent stem cell (iPSC) line was generated from a 36-year-old patient with sporadic Parkinson's disease (PD). Skin fibroblasts were reprogrammed using the non-integrating Sendai virus technology to deliver OCT3/4, SOX2, c-MYC and KLF4 factors. The generated cell line (CSC-43) exhibits expression of common pluripotency markers, in vitro differentiation into three germ layers and normal karyotype. This iPSC line can be used to study the mechanisms underlying the development of PD.
TypeJournal editorial
URIhttp://hdl.handle.net/1822/57878
DOI10.1016/j.scr.2018.01.007
ISSN1873-5061
e-ISSN1876-7753
Publisher versionhttps://www.sciencedirect.com/science/article/pii/S1873506118300072
Peer-Reviewedyes
AccessOpen access
Appears in Collections:ICVS - Artigos em Revistas Internacionais com Referee

Files in This Item:
File Description SizeFormat 
Marote A CSC43.pdf1,71 MBAdobe PDFView/Open

Partilhe no FacebookPartilhe no TwitterPartilhe no DeliciousPartilhe no LinkedInPartilhe no DiggAdicionar ao Google BookmarksPartilhe no MySpacePartilhe no Orkut
Exporte no formato BibTex mendeley Exporte no formato Endnote Adicione ao seu ORCID