Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/56679

TitleCurrent advances in solid free-form techniques for osteochondral tissue engineering
Author(s)Costa, João Bebiano
Silva-Correia, Joana
Reis, R. L.
Oliveira, J. M.
KeywordsOsteochondral
Scaffolds
Solid free-form
Tissue engineering
Issue dateJun-2018
PublisherSpringer
JournalBio-Design and Manufacturing
CitationCosta J. B., Silva-Correia J., Reis R. L., Oliveira J. M. Current Advances in Solid Free-Form Techniques for Osteochondral Tissue Engineering, Bio-Design and Manufacturing, Vol. 1, Issue 3, pp. 171-181, doi:10.1007/s42242-018-0017-y, 2018
Abstract(s)Osteochondral (OC) lesions are characterized by defects in two different zones, the cartilage region and subchondral bone region. These lesions are frequently associated with mechanical instability, as well as osteoarthritic degenerative changes in the knee. The lack of spontaneous healing and the drawbacks of the current treatments has increased the attention from the scientific community to this issue. Different tissue engineering approaches have been attempted using different polymers and different scaffolds' processing. However, the current conventional techniques do not allow the full control over scaffold fabrication, and in this type of approaches, the tuning ability is the key to success in tissue regeneration. In this sense, the researchers have placed their efforts in the development of solid free-form (SFF) techniques. These techniques allow tuning different properties at the micro-macro scale, creating scaffolds with appropriate features for OC tissue engineering. In this review, it is discussed the current SFF techniques used in OC tissue engineering and presented their promising results and current challenges.
TypeArticle
URIhttp://hdl.handle.net/1822/56679
DOI10.1007/s42242-018-0017-y
ISSN2096-5524
e-ISSN2522-8552
Publisher versionhttps://link.springer.com/article/10.1007%2Fs42242-018-0017-y
Peer-Reviewedyes
AccessRestricted access (UMinho)
Appears in Collections:3B’s - Artigos em revistas/Papers in scientific journals

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