Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/54787

TitleBio-based nanocarriers incorporating curcumin bioaccessibility and cell viability evaluation
Author(s)Gonçalves, Raquel F. S.
Martins, Joana T.
Duarte, Catarina M.
Vicente, A. A.
Pinheiro, Ana Cristina
Issue date6-Jul-2017
CitationGonçalves, Raquel F. S.; Martins, Joana T.; Duarte, Catarina M.; Vicente, António A.; Pinheiro, Ana Cristina, Bio-based nanocarriers incorporating curcumin bioaccessibility and cell viability evaluation. Book of Abstracts of CEB Annual Meeting 2017. Braga, 6 July, 36, 2017. ISBN: 978-989-97478-8-3
Abstract(s)[Excerpt] For decades, curcumin (Cur), a natural polyphenol product derived from turmeric (Curcuma longa) has been considered one of the most promising bioactive compounds due to its health benefits such as anti-inflammatory, antioxidant and anticarcinogenic properties. However, Cur application as functional compound in food products has been limited due to light, heat, and oxidation sensitive and mainly, to poor aqueous solubility which limit its bioavailability [1]. To increase Cur bioaccessibility and consequently, increase bioavailability, several carriers have been investigated, particularly nanocarriers. Among the various nanocarriers described in the literature, lipid-based nanocarriers may offer a promising tool to increase the stability, efficacy and safety of lipophilic compounds, namely Cur [2]. Moreover, the understanding of Cur-loaded nanocarriers’ behaviour under gastrointestinal (GI) conditions is fundamental to produce safe and customized nanocarriers with optimized bioactivity for oral consumption. The aim of this study was to comparatively analyze the impact of two different lipid nanocarriers incorporating Cur - solid lipid nanoparticles (SLN) and nanoemulsions (NE) – on bioaccessibility and Caco-2 cells viability. [...]
TypeAbstract
DescriptionBook of Abstracts of CEB Annual Meeting 2017
URIhttp://hdl.handle.net/1822/54787
ISBN978-989-97478-8-3
Publisher versionhttps://www.ceb.uminho.pt/Events/Details/3180
Peer-Reviewedyes
AccessOpen access
Appears in Collections:CEB - Resumos em Livros de Atas / Abstracts in Proceedings

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