Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/53439

TitleFruit-based carbon dots as fluorescent probes: in vitro and in vivo toxicity evaluation
Author(s)Dias, Cindy
Sárria, Marisa P.
Vasimalai, Nagamalai
Vilas-Boas, Vânia
Peixoto, J. M.
Espiña, Begoña
Issue date18-Sep-2017
CitationDias, Cindy; Sárria, Marisa P.; Vasimalai, Nagamalai; Vilas-Boas, Vânia; Peixoto, J. M.; Espiña, Begoña, Fruit-based carbon dots as fluorescent probes: in vitro and in vivo toxicity evaluation. MNE2017 - 43rd International Conference on Micro and Nanoengineering (Conference Booklet). No. PO131, Braga, Portugal, Sep. 18-22, 2017.
Abstract(s)New solutions for biomedical purposes are a major focus of interest for the development of new nanomaterials. In comparison to traditional metal-based quantum dots, photoluminescent carbon-dots are greater in terms of aqueous solubility, chemical inertness, simple modification and fluorescent proprieties. In this work C-dots derived from kiwi and avocado and synthesized using a green method were evaluated for their toxicity and bioimaging in vitro and in vivo. Normal and cancer cells lines, and zebrafish embryos were used as in vitro an in vivo models, respectively, either for toxicological profile and confocal imaging. Both C-dots showed toxicity profiles in the range of mg/mL concentrations inducing delays in zebrafish embryos development. Concentrations of kiwi and avocado C-dots used for confocal bioimaging were adjusted below the NOAEL accordingly.
TypeAbstract
DescriptionMNE2017 - 43rd International Conference on Micro and Nanoengineering (Conference Booklet)
URIhttp://hdl.handle.net/1822/53439
Publisher versionhttp://mne2017.org
Peer-Reviewedyes
AccessOpen access
Appears in Collections:CEB - Resumos em Livros de Atas / Abstracts in Proceedings

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