Please use this identifier to cite or link to this item:

TitleFruit-based carbon dots as fluorescent probes: in vitro and in vivo toxicity evaluation
Author(s)Dias, Cindy
Sárria, Marisa P.
Vasimalai, Nagamalai
Vilas-Boas, Vânia
Peixoto, J. M.
Espiña, Begoña
Issue date18-Sep-2017
CitationDias, Cindy; Sárria, Marisa P.; Vasimalai, Nagamalai; Vilas-Boas, Vânia; Peixoto, J. M.; Espiña, Begoña, Fruit-based carbon dots as fluorescent probes: in vitro and in vivo toxicity evaluation. MNE2017 - 43rd International Conference on Micro and Nanoengineering (Conference Booklet). No. PO131, Braga, Portugal, Sep. 18-22, 2017.
Abstract(s)New solutions for biomedical purposes are a major focus of interest for the development of new nanomaterials. In comparison to traditional metal-based quantum dots, photoluminescent carbon-dots are greater in terms of aqueous solubility, chemical inertness, simple modification and fluorescent proprieties. In this work C-dots derived from kiwi and avocado and synthesized using a green method were evaluated for their toxicity and bioimaging in vitro and in vivo. Normal and cancer cells lines, and zebrafish embryos were used as in vitro an in vivo models, respectively, either for toxicological profile and confocal imaging. Both C-dots showed toxicity profiles in the range of mg/mL concentrations inducing delays in zebrafish embryos development. Concentrations of kiwi and avocado C-dots used for confocal bioimaging were adjusted below the NOAEL accordingly.
DescriptionMNE2017 - 43rd International Conference on Micro and Nanoengineering (Conference Booklet)
Publisher version
AccessOpen access
Appears in Collections:CEB - Resumos em Livros de Atas / Abstracts in Proceedings

Files in This Item:
File Description SizeFormat 
document_47499_2.pdfCover37,35 kBAdobe PDFView/Open
document_47499_1.pdfAbstract112,96 kBAdobe PDFView/Open
poster20MNE_Cindy.pdfPoster4,62 MBAdobe PDFView/Open

Partilhe no FacebookPartilhe no TwitterPartilhe no DeliciousPartilhe no LinkedInPartilhe no DiggAdicionar ao Google BookmarksPartilhe no MySpacePartilhe no Orkut
Exporte no formato BibTex mendeley Exporte no formato Endnote Adicione ao seu ORCID