Utilize este identificador para referenciar este registo: http://hdl.handle.net/1822/52726

TítuloGRASPm: An efficient algorithm for exact pattern-matching in genomic sequences
Autor(es)Deusdado, Sergio
Carvalho, Paulo
sequence searching
Motif discovery
Sequence searching and analysis
RevistaInternational Journal of Bioinformatics Research and Applications
Resumo(s)In this paper, we propose Genomic-oriented Rapid Algorithm for String Pattern-match (GRASPm), an algorithm centred on overlapped 2-grams analysis, which introduces a novel filtering heuristic – the compatibility rule – achieving significant efficiency gain. GRASPm's foundations rely especially on a wide searching window having the central duplet as reference for fast filtering of multiple alignments. Subsequently, superfluous detailed verifications are summarily avoided by filtering the incompatible alignments using the idcd (involving duplet of central duplet) concept combined with pre-processed conditions, allowing fast parallel testing for multiple alignments. Comparative performance analysis, using diverse genomic data, shows that GRASPm is faster than its competitors.
Versão da editorahttp://www.inderscience.com/browse/index.php?journalID=155
Arbitragem científicayes
Aparece nas coleções:DI/CCTC - Artigos (papers)

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IJBRA 5404 Deusdado and Carvalho.pdfpaper (preprint)1,03 MBAdobe PDFVer/Abrir  Solicitar cópia ao autor!

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