Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/51975

TitleThe reaction of 2-(Acylamino) benzonitriles with primary aromatic amines: A convenient synthesis of 2-substituted 4-(Arylamino) quinazolines
Author(s)Marinho, Elina Margarida Ribeiro
Proença, M. Fernanda R. P.
Keywordsacylation
cyclization
heterocycles
4-aminoquinazolines
2-aminobenzonitrile
Issue date2015
PublisherGeorg Thieme Verlag
JournalSynthesis
Abstract(s)2-Substituted 4-(arylamino) quinazolines were prepared from 2-(acylamino) benzonitriles and primary arylamines by refluxing in either ethanol using trifluoroacetic acid as a catalyst or acetic acid. The 2-aminobenzonitrile was acylated by reaction with anhydrides, isocyanates, or ethyl chloroformate at room temperature.
TypeArticle
URIhttp://hdl.handle.net/1822/51975
DOI10.1055/s-0034-1380322
ISSN0039-7881
Peer-Reviewedyes
AccessRestricted access (UMinho)
Appears in Collections:CDQuim - Artigos (Papers)

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