Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/51842

TitleDisentangling working memory functioning in mood states of Bipolar Disorder: a systematic review
Author(s)Soraggi-Frez, Carolina
Santos, Flávia Heloísa dos
Albuquerque, Pedro Barbas
Malloy-Diniz, Leandro F.
KeywordsBipolar disorder
Emotion
Hedonic detector
Mood states
Working memory
Issue dateApr-2017
PublisherFrontiers Media
JournalFrontiers in Psychology
Abstract(s)Working memory (WM) deficits are often reported in patients with Bipolar Disorder (BD). However, it is not clear about the nature of these WM deficits (update or serial order processes) and their association with each BD states (euthymic, mania, and depressive). This review investigated the association between BD patient's states and the functioning of WM components. For this purpose, we carried out a systematic review fulfilling a search in the databases Medline, Scopus, SciELO, and Web of Science using specific terms in the abstracts of the articles that generated 212 outcomes in the restricted period from 2005 to 2016. Twenty-three papers were selected, completely read, and analyzed using PICOS strategy. The mood episodes predicted deficits in different components of WM in BD patients (the phonological loop or visuospatial sketchpad) and were associated with different WM processes (updating and serial recall). Lower cognitive scores persist even in remission of symptoms. This result suggests that WM deficit apparently is stage-independent in BD patients. Furthermore, findings suggest that the neutral point on Hedonic Detector component of WM could be maladjusted by BD.
TypeArticle
URIhttp://hdl.handle.net/1822/51842
DOI10.3389/fpsyg.2017.00574
ISSN1664-1078
e-ISSN1664-1078
Peer-Reviewedyes
AccessOpen access
Appears in Collections:CIPsi - Artigos (Papers)

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