Please use this identifier to cite or link to this item:

TitleHow do animals survive extreme temperature amplitudes? The role of Natural Deep Eutectic Solvents
Author(s)Gertrudes, Ana
Craveiro, Rita
Eltayari, Zahara
Reis, R. L.
Paiva, Alexandre
Duarte, Ana Rita C.
KeywordsDeep eutectic solvents
Cryoprotective agents
Issue dateSep-2017
PublisherAmerican Chemical Society
JournalACS Sustainable Chemistry & Engineering
CitationGertrudes A., Craveiro R., Eltayari Z., Reis R. L., Paiva A., Duarte A. R. C. How do animals survive extreme temperature amplitudes? The role of Natural Deep Eutectic Solvents, ACS Sustainable Chemistry & Engineering, Vol. 5, pp. 9542–9553, doi:10.1021/acssuschemeng.7b01707, 2017
Abstract(s)Recent findings have reported the reason why some living beings are able to withstand the huge thermal amplitudes between winter and summer in their natural habitats. They are able to produce metabolites decreasing deeply the crystallization temperature of water, avoiding cell disrupture due to the presence of ice crystals and overcoming osmotic effects. In vitro, the possibility to cool living cells and tissues to cryogenic temperatures in the absence of ice can be achieved through a vitrification process. Vitrification has been suggested as an alternative approach to cryopreservation and could hereafter follow an interesting biomimetic perspective. The metabolites produced by these animals are mostly sugars, organic acids, choline derivatives, or urea. When combined at a particular composition, these compounds form a new liquid phase which has been defined as Natural Deep Eutectic Solvents (NADES). In this review, we relate the findings of different areas of knowledge from evolutive biology, cryobiology, and thermodynamics and give a perspective to the potential of NADES in the development of new cryoprotective agents.
Publisher version
AccessRestricted access (UMinho)
Appears in Collections:3B’s - Artigos em revistas/Papers in scientific journals

Files in This Item:
File Description SizeFormat 
  Restricted access
6,66 MBAdobe PDFView/Open

Partilhe no FacebookPartilhe no TwitterPartilhe no DeliciousPartilhe no LinkedInPartilhe no DiggAdicionar ao Google BookmarksPartilhe no MySpacePartilhe no Orkut
Exporte no formato BibTex mendeley Exporte no formato Endnote Adicione ao seu ORCID