Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/51193

TitleGeneration of micro-sized PDMS particles by a flow focusing technique for biomicrofluidics applications
Author(s)Muñoz-Sánchez, B. N.
Silva, S. F.
Pinho, Diana
Vega, E. J.
Lima, Rui Alberto Madeira Macedo
Issue dateJan-2016
PublisherAIP Publishing
JournalBiomicrofluidics
Abstract(s)Polydimethylsiloxane (PDMS), due to its remarkable properties, is one of the most widely used polymers in many industrial and medical applications. In this work, a technique based on a flow focusing technique is used to produce PDMS spherical particles with sizes of a few microns. PDMS precursor is injected through a hypodermic needle to form a film/reservoir over the needle's outer surface. This film flows towards the needle tip until a liquid ligament is steadily ejected thanks to the action of a coflowing viscous liquid stream. The outcome is a capillary jet which breaks up into PDMS precursor droplets due to the growth of capillary waves producing a micrometer emulsion. The PDMS liquid droplets in the solution are thermally cured into solid microparticles. The size distribution of the particles is analyzed before and after curing, showing an acceptable degree of monodispersity. The PDMS liquid droplets suffer shrinkage while curing. These microparticles can be used in very varied technological fields, such as biomedicine, biotechnology, pharmacy, and industrial engineering.
TypeArticle
URIhttp://hdl.handle.net/1822/51193
DOI10.1063/1.4943007
ISSN1932-1058
Peer-Reviewedyes
AccessOpen access
Appears in Collections:DEM - Artigos em revistas de circulação internacional com arbitragem científica

Files in This Item:
File Description SizeFormat 
Munoz_Sanchez_et_al_BMF_2016.pdf1,33 MBAdobe PDFView/Open

Partilhe no FacebookPartilhe no TwitterPartilhe no DeliciousPartilhe no LinkedInPartilhe no DiggAdicionar ao Google BookmarksPartilhe no MySpacePartilhe no Orkut
Exporte no formato BibTex mendeley Exporte no formato Endnote Adicione ao seu ORCID