Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/51178

TitleLow cost microfluidic device for partial cell separation: micromilling approach
Author(s)Lopes, Raquel
Rodrigues, Raquel O.
Pinho, Diana
Garcia, Valdemar
Schütte, Helmut
Lima, Rui Alberto Madeira Macedo
Gassmann, Stefan
KeywordsMicromilling
Microfluidic device
Nonlithographic technique
Red blood cells
Cell-free layer
Issue date2015
PublisherIEEE
JournalProceedings of the IEEE International Conference on Industrial Technology
Abstract(s)Several studies have already demonstrated that it is possible to perform blood flow studies in microfluidic systems fabricated by using low-cost techniques. However, most of these techniques do not produce microchannels smaller than 100 microns and as a result they have several limitations related to blood cell separation. Recently, manufacturers have been able to produce milling tools smaller than 100 microns, which consequently have promoted the ability of micromilling machines to fabricate microfluidic devices able to perform separation of red blood cells (RBCs) from plasma. In this work, we show the ability of a micromilling machine to manufacture microchannels with dimensions down to 30 microns. Additionally, we show for the first time the ability of the proposed microfluidic device to enhance the cell-free layer close to the walls, leading to perform partial separation of RBCs from plasma.
TypeConference paper
URIhttp://hdl.handle.net/1822/51178
DOI10.1109/ICIT.2015.7125594
Peer-Reviewedyes
AccessOpen access
Appears in Collections:DEM - Publicações em actas de encontros científicos / Papers in conference proceedings

Files in This Item:
File Description SizeFormat 
aIEEE_ICIT_2015.pdf1,25 MBAdobe PDFView/Open

Partilhe no FacebookPartilhe no TwitterPartilhe no DeliciousPartilhe no LinkedInPartilhe no DiggAdicionar ao Google BookmarksPartilhe no MySpacePartilhe no Orkut
Exporte no formato BibTex mendeley Exporte no formato Endnote Adicione ao seu ORCID