Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/51097
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Campo DC | Valor | Idioma |
---|---|---|
dc.contributor.author | Singhal, Jaron | por |
dc.contributor.author | Pinho, Diana | por |
dc.contributor.author | Lopes, Raquel | por |
dc.contributor.author | Sousa, Patricia C. | por |
dc.contributor.author | Garcia, Valdemar | por |
dc.contributor.author | Schütte, Helmut | por |
dc.contributor.author | Lima, Rui Alberto Madeira Macedo | por |
dc.contributor.author | Gassmann, Stefan | por |
dc.date.accessioned | 2018-02-27T11:37:53Z | - |
dc.date.available | 2018-02-27T11:37:53Z | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 1876-4029 | por |
dc.identifier.uri | https://hdl.handle.net/1822/51097 | - |
dc.description.abstract | The most common and used technique to produce microfluidic devices for biomedical applications is the soft-lithography. However, this is a high cost and time-consuming technique. Recently, manufacturers were able to produce milling tools smaller than 100 m and consequently have promoted the ability of the micromilling machines to fabricate microfluidic devices capable of performing cell separation. In this work, we show the ability of a micromilling machine to manufacture microchannels down to 30 m and also the ability of a microfluidic device to perform partial separation of red blood cells from plasma. Flow visualization and measurements were performed by using a high-speed video microscopy system. Advantages and limitations of the micromilling fabrication process are also presented. | por |
dc.description.sponsorship | The authors acknowledge the financial support provided by PTDC/SAU-ENB/116929/2010 and EXPL/EMS-SIS/ 2215/2013 from FCT (Science and Technology Foundation), COMPETE, QREN and European Union (FEDER). DP acknowledge the PhD scholarship SFRH/BD/89077/2012, and P.C. Sousa acknowledges the fellowship SFRH/BPD/75258/ 2010, all attributed by FCT. | por |
dc.language.iso | eng | por |
dc.publisher | Bentham Science Publishers | por |
dc.relation | info:eu-repo/grantAgreement/FCT/5876-PPCDTI/116929/PT | por |
dc.relation | info:eu-repo/grantAgreement/FCT/5876-PPCDTI/135240/PT | por |
dc.relation | info:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBD%2F89077%2F2012/PT | por |
dc.relation | info:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBPD%2F75258%2F2010/PT | por |
dc.rights | openAccess | por |
dc.subject | Biomedical applications | por |
dc.subject | Blood cells | por |
dc.subject | Cell-free layer | por |
dc.subject | Cells separation | por |
dc.subject | Micromilling | por |
dc.subject | Microfluidic devices | por |
dc.title | Blood flow visualization and measurements in microfluidic devices fabricated by a micromilling technique | por |
dc.type | article | por |
dc.peerreviewed | yes | por |
oaire.citationStartPage | 148 | por |
oaire.citationEndPage | 153 | por |
oaire.citationIssue | 3 | por |
oaire.citationVolume | 7 | por |
dc.identifier.eissn | 1876-4037 | por |
dc.identifier.doi | 10.2174/1876402908666160106000332 | por |
dc.description.publicationversion | info:eu-repo/semantics/publishedVersion | por |
sdum.journal | Micro and Nanosystems | por |
Aparece nas coleções: | DEM - Artigos em revistas de circulação internacional com arbitragem científica |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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Jaron_MNS_2015.pdf | 992,05 kB | Adobe PDF | Ver/Abrir |