Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/49579

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dc.contributor.authorAgostinis-Sobrinho, C.por
dc.contributor.authorSantos, R.por
dc.contributor.authorMoreira, C.por
dc.contributor.authorAbreu, S.por
dc.contributor.authorLopes, L.por
dc.contributor.authorOliveira-Santos, J.por
dc.contributor.authorRosário, Rafaelapor
dc.contributor.authorPovoas, S.por
dc.contributor.authorMota, J.por
dc.date.accessioned2018-01-23T18:15:34Z-
dc.date.available2018-01-23T18:15:34Z-
dc.date.issued2016-
dc.identifier.issn0939-4753por
dc.identifier.urihttp://hdl.handle.net/1822/49579-
dc.description.abstractBackground and aim: Paradoxically, recent investigations have showed that adiponectin levels are inversely associated with muscle strength. However, to date, there is a lack of knowledge on the relationship between muscular fitness (MF) and adiponectin levels in adolescents. We aimed to examine the independent associations between MF and adiponectin levels in adolescents, controlling for several potential confounders.Methods and results: This is a cross-sectional analysis with 529 Portuguese adolescents aged 12-18 years. A MF score was computed as the mean of the handgrip strength and standing long jump standardized values by age and gender. We measured fasting glucose, insulin, HDL-cholesterol, C-reactive protein and adiponectin. Linear regression analysis showed a significant inverse association between adiponectin (Z-score by age and sex) and MF score, after adjustments for age, sex, pubertal stage, socioeconomic status, adherence to the Mediterranean diet, body mass index, HOMA-IR, HDL-cholesterol, C-reactive protein and cardiorespiratory fitness (unstandardized beta = -0.176; p < 0.005). Analysis of covariance showed a significant difference between the Low MF/Non-overweight group and the High MF/Non-overweight Group (p < 0.05) and between the Low MF/Non-overweight and High MF/Overweight Group (p < 0.05) (F ((5,) (523)) = 2.262, p = 0.047).Conclusion: Adiponectin circulating levels are inversely and independently associated with MF. In non-overweight adolescents, those with high levels of MF presented lower levels of adiponectin compared to those with Low MF. Likewise, overweight adolescents with High MF presented lower levels of serum adiponectin than non-overweight adolescents with Low MF. (C) 2016 The Italian Society of Diabetology, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition, and the Department of Clinical Medicine and Surgery, Federico II University.por
dc.description.sponsorshipThis study was supported by FCT grants: BPD/102381/2014 and BD88984/2012; The author Cesar Aparecido Agostinis Sobrinho was given Doctoral scholarship from Brazilian government by CAPES (Coordination of Improvement of Higher Education Personnel) (Proc: 9588-13-2). The Research Centre on Physical Activity Health and Leisure (CIAFEL) is supported by UID/DTP/00617/2013 (FCT). The author Rute Santos has a Discovery Early Career Research Award from the Australian Research Council (DE150101921).The authors gratefully acknowledged the participation of all adolescents and their parents, teachers and schools of the LabMed Study. They also acknowledge the cooperation of volunteer's subjects and the Research Centre in Physical Activity, Health and Leisure (University of Porto) for the sponsoring the LabMed Study.por
dc.language.isoengpor
dc.publisherElsevierpor
dc.relationinfo:eu-repo/grantAgreement/FCT/5876/147454/PTpor
dc.relationBPD/102381/2014por
dc.relationinfo:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBD%2F88984%2F2012/PTpor
dc.rightsopenAccesspor
dc.subjectAdiponectinpor
dc.subjectMuscular fitnesspor
dc.subjectAdolescentspor
dc.titleAssociation between serum adiponectin levels and muscular fitness in Portuguese adolescents: LabMed Physical Activity Studypor
dc.typearticle-
dc.peerreviewedyespor
oaire.citationStartPage517por
oaire.citationEndPage524por
oaire.citationIssue6por
oaire.citationVolume26por
dc.date.updated2018-01-23T15:08:29Z-
dc.identifier.doi10.1016/j.numecd.2016.02.011por
dc.identifier.pmid27048716-
dc.subject.fosCiências Médicas::Ciências da Saúdepor
dc.description.publicationversioninfo:eu-repo/semantics/publishedVersionpor
dc.subject.wosScience & Technology-
sdum.export.identifier2446-
sdum.journalNutrition, Metabolism and Cardiovascular Diseasespor
Appears in Collections:ESE-CIE - Artigos em Revistas Internacionais / Papers in International Journals

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