Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/49291

TitleA Ugi multicomponent reaction in the synthesis of N-cyclohexyl-2-(N-(4-methoxybenzyl)acetamido)-2-(thien-2’-yl)acetamide
Author(s)Costa, Susana P. G.
Raposo, M. Manuela M.
Esteves, Cátia Isabel Canavezes
KeywordsAmino acids
Chromatography
Multicomponent reaction
NMR
Thiophene
Ugi reaction
Organic chemistry experiments
Laboratory classroom
Issue dateDec-2016
PublisherRoyal Society of Chemistry
CitationComprehensive Organic Chemistry Experiments for the Laboratory Classroom (COCELC), 2016, Cap. 111, Experiment, 4.2.5.3. p 493-496
Abstract(s)The aim of this work is the synthesis of a protected unnatural amino acid using a Ugi multicomponent reaction, namely N-cyclohexyl-2-[N-(4-methoxybenzyl)acetamido]-2-(thien-2-yl)acetamide. Several experimental techniques will be considered such as thin-layer chromatography (TLC), vacuum filtration, and column chromatography on silica gel. The determination of the structure of the compound synthesized will be performed by NMR spectroscopy.
TypeBook part
URIhttp://hdl.handle.net/1822/49291
ISBN978-18-49739-63-4
Publisher versionhttp://pubs.rsc.org/en/content/ebook/978-1-84973-963-4
AccessRestricted access (Author)
Appears in Collections:CDQuim - Livros e Capítulos de Livros / Books and Book Chapters

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