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TitleAn array of highly selective Fabry-Perot optical-channels for biological fluids analysis by optical absorption using white light source for illumination
Author(s)Minas, Graça
Wolffenbuttel, R. F.
Correia, J. H.
KeywordsOptical filter array
Pptical absorption
Biomolecules analysis
optical absorption
Issue date2006
PublisherIOP Publishing
JournalJournal of Optics. a : Pure and Applied Optics
Citation"Journal of Optics. A : Pure and Applied Optics". ISSN 1464-4258. 8 (2006) 272-278.
Abstract(s)This paper describes a laboratorial microsystem (Microlab) used to measure the concentration of biomolecules in biological fluids. Rather than just one measurement channel, it comprises 16 optical-channels that enable the measurement of the concentration of 16 different biomolecules with the same device. An array of 16 optical filters based on Fabry-Perot thin-films optical resonators has been designed. Each optical-channel is sensitive in a single wavelength with a FWHM less than 6 nm and with a peak intensity higher than 86%. The 16 optical channels array fabrication requires only 4 masks, used with different deposition time. The Microlab can easily be tuned during fabrication to analyze different biomolecules only by adjusting the deposition times without affecting the device layout. A commercially available passband optical filter with a passband wavelength in 450-650 nm is used. The Microlab requires only a white light source for illumination due to the use of selective optical filters. The quantitative measurement of uric acid in urine is demonstrated. Such a device is extremely suitable for clinical diagnosis application in clinical laboratories and at a patient’s home because of its small size, low-cost and portability.
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AccessRestricted access (UMinho)
Appears in Collections:DEI - Artigos em revistas internacionais

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